Two issues come to mind.
Dosage is difficult due to the fact all cacti have a different concentration that can change depending on the time of year. There are several species being researched. Some are the same species but have such a different growing pattern eyebrows are raised.
Tea was used before and taste was undesirable. In addition the onset was very long as well as duration. Around three hours even though the glass was finished relatively quick with a length of fourteen hours. It was a control test to decide if that species was worth an investment. No citrus was used. Guessing a salt had to form internally before it could cross the mucus membrane? Not sure.
When reviewing Kash's tec the beauty is there. Fat solubles should remain in the NP layer during salting if titration is done correctly, so defatting is a waste of time. But there is also something to be said about the loss during purification.
When reading Practical LSD Manufacturer it was observed that a NP wash was the first step which lead to the hunch about the defatting step.
Purify with NP while the alkaloids are safe in acidic salt form in the aqueous layer. And avoid loss during crystal washing at the end. In addition to this, maybe the salt pulls would have less resins making them easy to weigh.
But in the end growing crystals is more fun then tea.
