DMT-Nexus member
Posts: 260 Joined: 05-Jul-2015 Last visit: 02-Nov-2024
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She finds it next to impossible to fall asleep when smalking changa before bed time. So naturally xanax comes to mind as a solution. Does anyone know if this is a safe combination ? How about melatonin? ( i am aware of the MAOI interaction lists but want to make sure  ) much obliged 
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xͭ͆͝͏̮͔̜t̟̬̦̣̟͉͈̞̝ͣͫ͞,̡̼̭̘̙̜ͧ̆̀̔ͮ́ͯͯt̢̘̬͓͕̬́ͪ̽́s̢̜̠̬̘͖̠͕ͫ͗̾͋͒̃͛̚͞ͅ
Posts: 1716 Joined: 23-Apr-2012 Last visit: 23-Jan-2017
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It's okay, you can even predose for trip anxiety. No interplay between MAOIs and Xanax. http://www.accessdata.fd.../2011/018276s045lbl.pdf
MEL is a tryptamine and will interact with MAOIS.
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DMT-Nexus member
 
Posts: 3968 Joined: 21-Jul-2012 Last visit: 15-Feb-2024
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Yes it's a safe combo as long as your benzo dose is within reason, however, the usual warnings of habitation and dependance must be offered. Benzos are useful only in the highest of moderation. Personally, I won't touch them, but if you do, please be careful. Sine experientia nihil sufficienter sciri potest -Roger Bacon
*γνῶθι σεαυτόν*
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xͭ͆͝͏̮͔̜t̟̬̦̣̟͉͈̞̝ͣͫ͞,̡̼̭̘̙̜ͧ̆̀̔ͮ́ͯͯt̢̘̬͓͕̬́ͪ̽́s̢̜̠̬̘͖̠͕ͫ͗̾͋͒̃͛̚͞ͅ
Posts: 1716 Joined: 23-Apr-2012 Last visit: 23-Jan-2017
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null24 wrote:Yes it's a safe combo as long as your benzo dose is within reason, however, the usual warnings of habitation and dependance must be offered. Benzos are useful only in the highest of moderation. Personally, I won't touch them, but if you do, please be careful. I think it depends on the person and their addiction affinity. FDA labeling says: Quote:Spontaneous reporting system data suggest that the risk of dependence and its severity appear to be greater in patients treated with doses greater than 4 mg/day and for long periods (more than 12 weeks). However, in a controlled postmarketing discontinuation study of panic disorder patients who received XANAX Tablets, the duration of treatment (3 months compared to 6 months) had no effect on the ability of patients to taper to zero dose. http://www.accessdata.fd.../2011/018276s045lbl.pdf
I actually doubt it causes problems if you take it sporadically. Source: product insert and own consumption.
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DMT-Nexus member
Posts: 3968 Joined: 21-Jul-2012 Last visit: 15-Feb-2024
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I agree with the first quote and statement but take issue with the second. Anyone taking a benzo of any kind for two weeks straight is going to deal with some withdrawal. 12 weeks, and they'll go psychotic if they stop. This is also from my own consumption, and anecdotally from friends. That said, taking a Xanax to sleep once in a while isn't going to harm you. It's regular use that can become troubling. Sine experientia nihil sufficienter sciri potest -Roger Bacon
*γνῶθι σεαυτόν*
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xͭ͆͝͏̮͔̜t̟̬̦̣̟͉͈̞̝ͣͫ͞,̡̼̭̘̙̜ͧ̆̀̔ͮ́ͯͯt̢̘̬͓͕̬́ͪ̽́s̢̜̠̬̘͖̠͕ͫ͗̾͋͒̃͛̚͞ͅ
Posts: 1716 Joined: 23-Apr-2012 Last visit: 23-Jan-2017
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I have nothing to add.
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DMT-Nexus member
Posts: 260 Joined: 05-Jul-2015 Last visit: 02-Nov-2024
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Thanks for the advice travelers my only relation with benzos is they getting me to sleep after a trip... thanks for the care though Quote:
MEL is a tryptamine and will interact with MAOIS
Thats news to me Does it mean that melatonin + harmalas will be psychoactive ? cheers 
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xͭ͆͝͏̮͔̜t̟̬̦̣̟͉͈̞̝ͣͫ͞,̡̼̭̘̙̜ͧ̆̀̔ͮ́ͯͯt̢̘̬͓͕̬́ͪ̽́s̢̜̠̬̘͖̠͕ͫ͗̾͋͒̃͛̚͞ͅ
Posts: 1716 Joined: 23-Apr-2012 Last visit: 23-Jan-2017
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monomind wrote:Thats news to me Does it mean that melatonin + harmalas will be psychoactive ? cheers MAOIs will inhibit the metabolizing of MEL in your body until they will be metabolized themselves, so yes. Universecannon thinks it's save and will produce lucid dreams, search for "Universecannon melatonin maoi". Or PM him. Since MEL is a hormone produced by your body, I'm pretty sure it won't hurt if you do it once, the body just has to deal with an MEL overload in your brain. Large doses of MEL are regarded as save in a short-term fashion, not a huge risk to OD here. But that's just my random internet opinion, no research papers to back that up.
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