Has anyone had experience with the two combined?

A friend of a friend took both, and has been extremely paranoid as of late. Is it the shroom low and it just needs to be waited out, or is there a better fix?

What was the dose and species of mushroom, and how long ago was it? What were the nootropics in question? Dose? I find that after a very powerful psilocybin trip, I can be a little bit...out-of-it (for want of a better term) for 1-2 days afterwards, before the afterglow sets in in earnest.

There are a LOT of nootropics out there and it's impossible to do a definitive analysis of the possible interactions between all of them and psilocybin, but, in general, most nootropics seem to be pretty benign (I'm convinced that most of them are placebos, at least, those that you can get OTC), so I doubt that the addition of the extra compound the psychedelic one is all that relevant.

Blessings
~ND

I've used psilocybe mushrooms and other psychedelics during courses of taking various nootropic plants/supplements with interesting results. Some improvements in energy, focus, attention.. but also some improved neutrality during the comedown. Some nootropics enhance VMAT potently so. Caution in choosing the right nootropic/dose is important.