Freebased crushed rue smoked just prior to smoked Vilca really enhances it nicely... and extends it very well.
I imagine 10x would do the same for insufflation. Is the 10x a freebase or salt? If it is the latter; try sublingually dosing it prior; as I believe it is common for the natives to chew Caapi for Vilca potentiation. Harmalas also combat vasoconstriction.
Caapi is sometimes mixed into the snuff itself...
I hear harmalas are very effective when used sublingually for potentiation (but never oral activation). Holding fresh-crushed rue seed under the tongue can really amp up a Vilca session when used just prior to the journey; with the powder of ~12 seeds held sublingually for 7 minutes then swallowed and immediately repeated a coupled times.
A few drops of Lemon essential oil mixed with olive oil in a capsule or make lemonade before/with the harmalas is helpful in eliminationg seretonergic nausea.
Blessings.
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Without prejudice.