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Remember the 'incence' Spice?? well its got a designer cannabanoid in it!! Options
 
Jorkest
#1 Posted : 12/17/2008 5:23:06 PM

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STS is a community for people interested in growing, preserving and researching botanical species, particularly those with remarkable therapeutic and/or psychoactive properties.
 
Infundibulum
#2 Posted : 12/17/2008 5:33:10 PM

Kalt und Heiß, Schwarz und Rot, Kürper und Geist, Liebe und Chaos

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Nice find! SWIM's FOAF has loads of JWH-015 and JWH-018 in his lab because he's working on endocannabinoid receptors and their endogenous ligands.

But he never really tried to smoke them, maybe he should.

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bufoman
#3 Posted : 12/17/2008 5:44:12 PM

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I have been wondering about the effects of these compounds. They look like they could be rather easily synthesized and are not analogues as the structure is very different than any resorcinol derivatives. Furthermore they seem like very good lead molecules for future cannabinoid agonists. If SWIM tries it out please let me know. This is a fascinating field. the endocannabinoid is vast and controls most of the brains of chemical systems. ZThe potential for selective therapeutics is immense. I worked with endocannabinoid derivatives for a while on the chemistry end though.
 
Infundibulum
#4 Posted : 12/17/2008 6:15:24 PM

Kalt und Heiß, Schwarz und Rot, Kürper und Geist, Liebe und Chaos

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When he got them he was looking for specific CB1 and CB2 agonists. Only JWH-015 is specific to CB1 (with slight specificity to CB2) however. JWH-018 being not selective however turned not very useful to him but anyway.

Now his research interests have moved a bit so he's using mostly pure anandamide and arachidonoylglycerol nowadays. He hasn't tried to smoke them either. They look like yellow oils however, pretty appealing.

Too bad on the other time that he doesn't like weed or being stoned.


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acolon_5
#5 Posted : 12/17/2008 6:20:53 PM

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Not at all suprised. The effects were just too damn close to mj. Even the side effects fit almost to a T.

A tad upset that it came out...now all the US has to do is ban those cannabinoids and poof, spice (and almost all of the other "incense" brands will be illegal in the US...

Sad
The Spice extends life
The Spice expands consciousness
The Spice is vital for space travel
___________________________________________________________________________________________________
Never underestimate the power of STUFF!


I am certifiably insane, as such all posts written by me should be regarded as utter nonsense or attempts to get attention.

I don't know SWIM and personally don't trust him at all. If SWIM is posting, most likely I will not respond...as I said, I don't trust the guy. YOU I trust, but never SWIM.
 
Observant
#6 Posted : 12/17/2008 6:24:04 PM

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Thats the analysis rep of thcpharm

http://usualredant.de/dr...-pharm-spice-jwh-018.pdf
Had he more quickly realized just who they were,he would have shown them more respect.Had he tried harder to fathom their brilliant minds,he would have taken more of their teachings to heart.Had he more clearly understood the purpose of their being,
he would have more vigorously tried to assist them.They were truly honorable; he was sadly prejudiced.
They were exceedingly well informed; he was grossly ignorant.They were totally indefatigable; he so often, and so quickly,gave up. Still, for many years there was a strong inter-species alliance between the Eleven-Eleven of the Half-way Realm, their Seraphic Associates,and their flesh-and-blood friend, a common mortal. Much was accomplished, many profited, and, there’s only one regret...They could have achieved so much more...
All Hypnotizing Hypnotizes Hypnotizing
 
 
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