I can't seem to find information on this. I'm on 45 mg methadone but I plan on getting off of it soon and would like to start working with caapi in a similar way as Ibogaine. For now though I would like to make Changa and smoke that as I come off the methadone. Would this be dangerous?

I would advise strongly against this-get off the methadone first..but also wait for others with more medical knowledge that can verify this for you..and then once you are clean for the required ammount of time maybe work with ayahuasca-forget smoking if you want to work through some stuff. I would highly reccomed you work with ayahuasca to deal with issues of addiction beyond the physical. Smoking changa is great and all..but you can work through alot more with ayauhasca IMO.

No, just no. Spice is a very powerful substance and I wouldn't risk mixing it with opioids.
That being said, it probably wouldn't be that dangerous since DMT is relatively low risk overall and your methadone dose works for you. Therefore you probably could do this with little risk to yourself, but I still wouldn't. In the end its your decision.

^the op is asking about harmalas with methadone not spice..spice is fine..at least there wont be life threatening interactions there, might be better though with spice as well once off methadone..harmalas and methadone though-no way dont risk it.

Oh I thought he was talking about smoking changa as he comes down from the methadone(but still on it I'm guessing). I don't know enough about harmalas but I wouldn't risk it.

My intention was to smoke Changa while I'm dosing down to come off of the methadone and then work with Ayahuasca after it's out of my system. I've smoked non-MAOI Enhanced Leaf (mullein/mint/Spice) while on methadone so I think I'm ok there. I'm basically just wondering if the same dangers apply to smoking the MAOI while on methadone.

The combination of ORAL RIMAs and opioids, according to the BNF, has the potential for adverse reactions, namely CNS excitation or depression (resulting in high or low blood pressure).The BNF mentions pethidine and DXM in particular, but says this can also be the case with fentanyl, morphine and 'possibly' other opioids, and says concomitant use of RIMAs should be avoided.

Strangely enough, I cant find a section in the BNF pertaining to smoked/vaporised RIMAs ( ), but I would say that its not a risk thats worth taking.

Straight FB DMT vaporised with opiates is a combination that Ive found to be very pleasant.

Thanks corpus, I will hold off on the caapi smoking till I'm off the 'done. I like to have out-of-body experiences but I'm not ready for a permanent one quite yet.

Thanks everyone, I appreciate the input.

Have you tried the Ibogaine method of getting over the monsterous withdrawl hump that methadone leaves you with having to overcome?
If not, thats the first thing to get onboard in doing......
Being on 47mg of methadone a day and after several times trying to ween off their(the KKKlinic) way, I have decided that obtaining a few grams of the iboga powder,(not the isolated pure chemical ibogaine hcl) is my best bet in leaving the opiate monkey behind and hopefully with a geographical relocation and my newfound relious viewpoints towards psilocybe cubensis and especially towards pharmahuasca (syrian rue seeds and mimosa hostilis) will be everything I need to put this methadone lifestyle and its dead end outcome in my rearview...

hi hun i was on methadone for years ofr chronic pain and had no problem with a fairly moderate aya jurney. im not saying it was a good idea but im definatly not saying it was a bad idea cause i had a beautiful journey.

from my knowledge and experience with very small doses there is no adverse interaction between smoked harmalas and poppy tea. Which of course is not as strong as methadone.

Go slow, try a very small dose, try a slightly bigger one a few days later, take notes, repeat

Going big with this combination can indeed kill you.




if you are dealing with methadone withdrawal and want to use iboga to get over it i suggest you pay a doctor to monitor you during the session

in any case you have to tamper down your methadone use over a longer time period and then switch to heroin, morphium or poppytea for the last week before the iboga session


quite a few people with methadone problems have extended their trip to the other side indefinitely, careful there

I have read that demerol and maoi is super bad.

be careful... oh i see now that you are gonna hold off. Good call... I don't think shrooms and the dozo is bad though....

i have experience with taking psilocybe cubensis on methadone which I found less spiritual than usual. I have also experienced 4-aco-dmt on methadone which gave a really bad reaction and felt like it was suffocating me during the come-up (which I obviously never repeated again).
For this reason I would never, I mean NEVER consider taking ayahuasca while on or coming off of methadone until I was certain it was completely out of my system. But that's just me personally.
I've always been specifically sensitive to harmalas and seem to get an inordinate amount of sedation from them that I find uncomfortable and it just doesn't appeal to me as something I'd want to pile on top of an opiate. I've also overdosed on Syrian rue before, which has always resided in my memory as the most excrutiating ayahuasca trip and most painful six hours of my life.
That being said, as others have mentioned... smoking freebase DMT can be an extremely pleasurable experience while on an opiod as well as various other chemicals (I personally really enjoyed my trials with smoking dmt while under heavy doses of ketamine).
But anything involving maoi's (including even moderate inhibitors such as AMT for example)
I would strongly reconsider mixing with methadone. I'm not sure if there's any pharmacological certain proof of it being a dangerous interaction (such as serotonin syndrome from mixing mdma with maoi's) but I still wouldn't take the risk.

Also, any lengthly psychedelic experience on methadone, be that natural or synthetic, whether safe or unsafe... I have always found to be a more blunt, more duller and certainly MUCH less of what is usually a revitalizing spiritual journey.
As a tool to overcome addiction to opiods, especially methadone and heroin...
I owe my entire life to the tryptamine family.
peace

I just met a good fella and spent a week with him in the community my girlfriend and I were living. He was an ex heroin addict and has a couple dozen ayahuasca ceremonies under his belt while he was on methadone.

He was finally warned by a spirit that he would not be allowed to journey any longer until he stopped taking the methadone and cleansed his system. He did head this advice and has been clean for 8 months off methadone so came to Peru to continue his work with aya and says the experiences now are much more vivid with less of a heavy blurry feel to them.

Not sure if that helps you at all. Sounds like smarter minds have weighed in on the dangers of changa and opiates although i have smoked changa and drank ayahausca with opiates in my system back when I was taking prescription pain meds. But experiences do not trump data so go the safe route and just wait.

Lame combo.

I've had oral MAOI while I was on buprenorphine. I didn't get any adverse reactions. The dose was 4 mg buprenorphine a day. Then I took about 140 mg of harmala orally and no side effects.

I wouldn't advise to do it still.

A friend of mine was frequently taking spice and methadone together last year when I introduced it to him I told him about aya and I told him he should be clean just incase aya makes you puke anyways you don't wanna be puking from opiods and aya regardless any other adverse effects plus with that dose of methadones, you might potentially risk cns depression I would feel. But as others have said If your looking to do dmt then try just smoking til you're off the methadone, my buddy did that frequently with no adverse effects.

I'm no doctor, not giving advice, just experience. I've been on methadone the entire time I've been experimenting with spice. I have limited exp with harmala, just recent smoking of rue with herb.
I think that for me, having just gotten back into psychs after a20 year absence, that the dmt flash enabled me to become comfortable enough w with them again to try a deeper, more introspective exp like aya.
I really don't think low dose rimas like on changa will potentiate your methadone. Especially under 60 mgs .
It may give you the freedom inside you need. Personally,I went spice first,rue, plan on aya when I get below 1mgs, then ibogaine at the end of this trip.
Good luck brother,I hope you can tell us you are free soon.
Hey I apologize if my recent posts are a little writer weird, I'm having trouble reading entire threads on a little screen, I'm nowhere near a terminal l.
By the way, I'm curious, are you fellow KKKlinicans (I like that) in CRCb brand treatment. That effin company bought every clinic here almost, and that's a lot. Y they are the world's largest treatment provider for methadone. Can you say drug cartel?

You should know that combining MAOIs with Methadon would almost certainly lead to your death. The internet is full of the information you seek. Google "MAOI diet" for instance.
Wikipedia's article about MAOIs lists a whole number of drugs & foods to be avoided when
ingesting MAOIs. Amongst them opiates, amphetamines, cocaine, Benzos and a whole range of other drugs, that, in combination with MAOIs, will most likely kill you.


Why not just smoalk DMT? Without MAOIs? Being on Methadone you'd probably narrow your
consciousness too much to get the best out of your DMT experiences.
But I assume you wish to have spiritual/therapeutic DMT experiences to ease up/guide the psychologically rough opiate-withdrawal you're going through?

Smoking DMT from base-pipes or from Joints(sandwitched between tobacco &/or Cannabis) should do that trick just fine. As far as I know Methadone & DMT don't cause dangeriously adverse reactions, though I could be wrong; I'm no doctor. But I'm sure someone here or google can help you find that out.

I assume you're getting a prescription for your Methadone from some
kind of Opiate-withdrawal clinic? Perhaps you can ask a physician at that clinic
wether DMT causes adverse reactions when combined with Methadone or not?

I think the above comment mybe an exaggeration. From all the research i have done on methadone and MOAIs it seems there is the possibility of serotonin syndrome which, in worse case scenarios, can lead to death.
There are many links about it, some say it is not a problem and some do. But i have never found a site that says that if you combine the 2 you will almost certainly die!! Can you post a link i would be interested to read it.
Personally i don"t feel it is worth taking the risk mixing the 2.