Hello,
i know somebody that is interested in a pharmahuasca experience. The person has a lot of experience with Changa, smoked Freebase, and IM/Snorted fumarate.
I plan on taking an MAOI, yet, i am unsure about what to recommend.
I know that there are several different MAOI's one may choose, that they have different strengths and binding affinities, and that some bind reversibly and some irreversibly.
I have two approaches i would like to run past you more experienced users.
1st, i plan on dosing MAOI's for two days before the experience begins, and to maintain a high concentration of inhibited MAO. Basically i would like to establish a complete block of the MAO enzyme system. This can be done with irreversible MAOI's, or by a constant low dose of other reversible MAOI's (harmala alkaloids). This sounds like the more challenging way, since i have to watch my diet the month we plan on taking the journey. However, the benefits are that i am guaranteed to be effected by the DMT, since all the enzymes breaking it down are shot prior to ingestion.
2nd, i could plan on dosing a moderate to strong dose of MAOI before the experience. This sounds like i need to pay attention to my time variables a lot, and the MAOI i take may not be strong enough.
For MAOI's, what are the common dosages that are suggested? I read around a bit and found it varies WILDLY.
The person that will be doing the experience is a 125lbs individual, which plans to consume around 80mg of DMT.
Would there be a benefit at all, from pre-loading with MAOI's the days prior, to maintain a level of MAOI's in the body?
what would you suggest for a moderate to strong experience?
any input appreciated
