The following is a description of a test subjects first experience with smoked DMT (65mg).

The subject had done an experimental dose of 10mg 3 days prior.

The subject decided to do it alone, except with his dog. He loaded his pipe and sat down.
He described trepidation. His hands were sweaty. He was had that feeling of being on a roller coaster and still climbing the first hill. He was scared. The subject made sure all the electronic devices in the room were off, except for the music. He played "Wave Mantra".
The subject sat down and let his thoughts settle. He took a very big pull from his pipe, and held it in while he sank into the floor and felt his muscles grow weak. When the subject exhaled he noticed thick white vapor. He took another big hit, and swallowed a little air with this one. This one was harder for him to hold in. The buzzing came. His muscles were very weak now, he exhaled and laid back. The ceiling which is typically a drab drip plaster ceiling arranged itself into a tiled pattern first and then revealed barbed tentacles. The subject described these life forms as resembling something between an octopus and a giant carnivorous plant. The subject smiled. The subject questioned if he was going to experience "breakthrough". He was terrified. He told me he summoned the guts to sit up, and a like a severely disabled person attempted to operate his lighter and bowl for a third final hit. He did it, barely. The buzzing grew louder, and he quickly laid back down and the giant organism in the ceiling came closer to him. The subject had a complex variety of feelings, joy, happiness, terror. It occurred to the subject that there may be insects. Millions of them. He reminded himself that this would be OK to have the bugs crawling all over him. They never did. The subject reminded himself to breath, his heart rate was like a rapid drum. The subject said he knew because the sun was still up he may not experience as strong hallucinations as at night, so he closed his eyes for some CEV. There was a room, with a stairway and a door. The walls, ceiling and floor separated, and there was a vast darkness beyond. The darkness of the beyond reminded the subject of some things he had been carrying with him for a long time. The subject had devoted considerable time and energy into studying Castaneda and his books. Suddenly the subjects life time was presented to him, and he was struck by it's meaninglessness. All his passions, battles against authority, fears and true loves, meant nothing. Then he saw the lifetimes of many others, all around him everywhere, human beings with meaningless lives. The subject cried, but was at the same time glad to see this. Then a summation of everything he had read was presented to him. The subject described a large question "But what if?". He asked himself who was judging the meaning of these lives, he was. He asked himself what the experiences were for. Something took those experiences away from you when you die. What if that is all it wants, is those experiences, and nothing more, not your life. The subject described seeing these human lives on a desert landscape. He then saw a man in the same landscape, standing before him. They were on a mountain. The man looked like him. The sun was setting. The man was smiling. The man was full of joy, ecstacy. Then the man jumped off the cliff. The subject closed his eyes, and there was a large flower before him. The flower was one of those one or two petal types that resembled an organic cup, with a large phallic thing protruding out of it. There was another extension of the phallic thing and it was touching the subject. There were stairs leading into the flower. The subject said the flower wanted him to go into it. "I can't" he said. The subject said he had to struggle to maintain the vision, it started to flickr and fade away. The subject opened his eyes and watched swirls on his ceiling. The subject was filled with love and joy of life. "Here and now" he said.
He went for a long walk and watched the sun set.


After reviewing the subjects report it sounds more like an ayahuasca trip than some of the DMT reports I've read.