I was wondering how one would go about extracting alkaloids from Kratom leaves. I haven't found any reliable teks on the internet, and was wondering if any members here have attempted such an extraction on this substance.
With regards to extraction, I was thinking that an A/B on raw plant matter, possibly followed by a mini-A/B to remove any leafy components of the plant. Which NPS would be best for pulling Kratom Alkaloids? Naphtha/heptane would be ideal as freeze precipitation would be possible but idk how soluble freebase mitragynine and 7-HO mitragynine would be in such a solvent.
Also, I was wondering how stable Mitragynine and 7-HO mitragynine would be in a strongly basic (1 M NaOH or equivalent) solution and what effect temperatures of 120-212 degrees farenheit would have on the structures of the alkaloids as I know that some compounds will degrade, isomerize, and otherwise change in nature of structure and function when exposed to such conditions.
I would appreciate the input of the community on this subject as I have become interested in extracting Kratom Alks myself and have yet to come accross a trustworthy tek on how to do it. 10X, 20X etc extractions don't interest me-i'm curious to know if the alkaloids themselves can be isolated from plant matter for more accurate dosing.
Thank you for your time and input,
-Godsmacker
'"ALAS,"said the mouse, "the world is growing smaller every day. At the
beginning it was so big that I was afraid, I kept running and running, and I was glad
when at last I saw walls far away to the right and left, but these long walls have
narrowed so quickly that I am in the last chamber already, and there in the corner
stands the trap that I must run into." "You only need to change your direction," said
the cat, and ate it up.' --Franz Kafka