I read one Trip report about this combo on erowid i think.
Has anyone tried it ?

humm not sure. This maybe an interesting combination. My guess though it would not do much as melatonin is so mild as is. Maybe this in combo with DMT would be interesting. SWIM has tried melatonin and DMT it def seemed to lengthen the experience and alter it a little. It was not placebo as the experiment was replicated...

Ihave taken does of 3mg melatonin and then smoked a bowl of rue seeds...i got the tryptamine pineal buzz fealing and increased relaxation..not a trip though..maybe if I took more.

I smoked Harmaloids and took 3mg Melatonin sublingual before going to sleep , not much more than usual imagery.
Maybe a full MAO Inhibition through Caapi Brew - and then smoking extractedMelatonineFreebase either with or without DMT.

Someone in this Forum Mentioned a while ago it was possible to make a kind of 'Sleepahuasca' - which initially made me think about the combination.


This was the Erowid report - the Melatonin Dosage the Author gives is chosen randomly i suppose.

i used melatonin as a dream catalyst, then during a dream i went to the amazon and was given calea zacatechi, i bought it, tried it, loved it. in conjunction with melatonin too!

In spite of it's chemical relatedness (i believe it's something like acetyl,5MeO-tryptamine) to DMT, i'm pretty shure that melatonin has no psychedelic or otherwise narcotic effects.
It's been tested as a birth-controll pill for men, since in amounts of over 100 mg it drastically and temporarilly reduces fertility without causing harm. Even in extremely high doses of half a gram it did not cause anything spectacular as far as i know. There might be some unknown interaction with tryptamine psychedelics but on itself it has no psychedelic property's. I have taken it as a sleeping aid myself and have never felt any other effects then sleepyness from it, even when i took 20 mg.

One thing SWIM hates about smoked DMT is that after the peak he feels like he’s taken melatonin. He gets that same melatonin style sedated body feeling from it. He hates it. He always has to drink coffee afterwards to shake it off.

this is quite a good area to explore,
ancedotally, before the brain prepares for its nightly subconcious journey,
it floods the brain with melatonin, giving the seritonin system a rest, and preprase the head
for its neural clensing, which, if i understand correctly, is being down by our naturall
nn,dmt, and 5meo-dmt, causing "dreams", this is all part of the brains sicadian rythm, which is nessacary to maintaing a healthy and functional brain/nervous system.

intrestingly more so is that the brain metablisis melatonin with pinoline, 6-methoxy-1,2,3,4-tetrahydro-β-carboline, the pinal glands natural b carboline,, aye what?

any one corretct me if these persumptions are out of the ball park

....any who, i regularly travel and screw up my sicadian rythm, and found melatonin to be the best to reset this system, and have ainterstying time doing it.

one night swim was really thinking about this intresting brainyausca happeing every night, and reading the invisible landscape instilled the dreamers confidence, so what swim was going to do was take 15 mg melatonin, (about 5x recomended dose), and really tried to stay awake,

in the end i got to about a +2, a decent plus +2, i could still make out all the nessecary definitions of the physical place i was, but all the objects and meanings they carry where whorling and frothing with life, and focusing on this bush or that bush, brought that object to life, with its own sort of dialoge that i could actually hear, as well i could hear things i wasnt thinking, suggestion or persusive things
when i tried to make my way to my room at about the ass crack of dawn, the house was very difficult to navigate, my mental map of the place was jsut not there, and teh dakkend house was a glow with those enrgy worms that surround everything,

when i laid down finally too sleep, i felt intense vertigo, like i was falling through infiitiy, a really intense WHOOSH accopmanied by the physcial "strobe light" feeling

This is a interesting subject. I do not believe Melatonin on it's own has any psychedelic properties, but I am happy if I am wrong. But what about a chemical way to reduce Melatonin to an other tryptamine, perhaps a psychedelic one? Melatonin does contain the Tryptamine skeleton, so at least theoretical it should be possible. Will this be possible, if yes, how?

sometimes mixing 3mgs melatonin with a low dose of aya is nice. it really helps in relaxing into the trance state, as well as maintaining single thought streams/groupings as opposed to the jumping around that normally occurs. also, the transition to sleep after a few hours comes real naturally (go figure), though the following morning is just a tiny bit more groggy than the usual aya renewal.

as for potentiating - compared to similar doses of aya without the mel - I'd speculate it's due to focus/concentration rather than the physical presence of melatonin. great mix nonetheless.

can't really speak for harmalas and melatonin alone. I find the harmalas to be a bit stimulating and melatonin to be only slightly useful in bringing sleep, so this combo hasn't really worked it's way into my diet.