I'm not a huge fan of Hamilton Morris (or VICE, for that matter), but my attention was piqued when a friend of mine pointed me towards a new episode of Hamilton's Pharmacopia devoted to a potentially new family of psychedelics.
Apparently, there are people in South Africa who are using the antiretroviral anti-HIV medication Efavirenz as a hallucinogen.

Hamilton himself dosed with a standard therapeutic dose and found it to be actively psychedelic (he compared it to mescaline), although apparently it had a terrible crash. Interestingly, the drug (which has been shown to have 5-HT2A agonist activity) bears no structural similarity to any of the three existing psychedelic families, which suggests the existence of a possible fourth family.

A family that is unresearched and, tantalizingly, completely unscheduled.

Watch the documentary here


Blessings
~ND

http://www.ncbi.nlm.nih.gov/pubmed/23702798

Efavirenz has a range of effects on a variety of neurotransmitter systems; patients who are on this need to be warned about its ability to cause depressive symptoms which can result in suicide attempts.

I watched a documentary on this stuff as well, though in the video i watched they were claiming the effects were primarily from the heroin that is usually mixed into a concoction containing the HIV medication....pretty interesting stuff...

Thanks, that was very interesting.

"...But when you say I'm effivirenz..."