Also, talking about doses in terms of freebase standardises the figures a bit. Fumarate weighs about thirty per cent more per DMT molecule equivalent.

ok, thanks guys, I think I understand that a bit more.

I'm in the process of making Fumarate from my freebase and looking to use Syrian rue as a MAOI

Don't know how well this work so if anyone with better knowledge could back it up it would be great. Anyway I heard of someone that had issues feeling the effects of dmt in pharmahuasca that tried to drink the dmt with lime juice and said it kicked in much faster and more efficiently. Might be worth a try..

Anything acidic (but still edible ) should work.

There is tons of information presented here about the timing and methods of consumption of DMT substances and MAOI material.

Haven't seen a mention of outside confounding factors.

I couldn't get much of any result from Ayahuasca consumed in a variety of ways, smoked DMT or even mescaline for awhile because I was on a gabaminergic substance, Gabapentin. I confirmed the relationship between the GABA receptors and psychedelic results by going off the substances then completely halting a strong Ayahuasca trip with Phenibut.

Gabaminergics build up to more appreciable levels depending on the duration of their half lives so actual levels can be much higher than doses (like other substances like methadone or phenazepam).

It was hell going off that garbage but worth it. Now I trip nicely.

IDK if these are a confounding factor for you but I did isolate them as such for me and eliminate their hinderance of my effects.

Warning: discontinuing GABA drugs can be dangerous and should only be done under the care of a doctor.

I've had extremely brilliant and powerful trips off 2 grams powdered rue and 100 mg dmt freebase, I call it my triple 7 ix I get 3 gel caps, take 700 MG rue in one, and 700mg rue in another, let those sit on the side, the 3rd I fill with 600 mg rue and 100 mg dmt. I dose as follows, 1 rue ONLY cap on an empty or nearly empty stomach, then wait 15 mins take the second rue cap, wait another 15 mins then I take the last mixed cap wait about 20 mins and eat a small bit like a few peices of bread and drink some water, and this brought on AMAZING trips for me, with full blown OEV and CEVs and psychedelia that brought me to tears. (happy tears) However I had one experience with it when I did something similar I was testing the lowest amount of rue I could take to get the oral dmt effects 2 grams seems to be my minimum limit needed because with 1 gram, then 15 30 mins later 100 mg dmt, I had VERY LIGHT effects, waited it out for about an hour to see if it would increase, and when i noticed it almost basically drop to baseline out of thin air within 2 hours of final ingestion I dosed another 1 gram rue to see if that would kick it back in, whihc for a short period it did, all in all the exerien ce there was basically i had minor body buzz, ONLY BARELY VISIBLE BUT NOT PLACEBO FRACTAL (black and white) CEVs but no OEVs, I was also experimenting with other tryptamines and phens, in the prior days and weeks, so this could have been a tolerance issue, but I mean I and 2 other people on 3 trials for me had the exacxt same effects (other than the general experience but in terms of depth, visuals and psychedelia, the 3pl 7 ix is my sweet spot, not too over the top, stronger than mushrooms, but comes on in waves like shrooms, but way more colorful geometic, and playful, no paranoia. Everyone is different though




As you said freebase will eventually turn into hcl in stomach anyways, to avoid the taste of all of them was my intent with trying gelcaps as mentioned above... also i find taking it all in dry for rather then the tradition huasca tea give little to no nausea where as the other two times, I tried it in liquid 1st time I felt almost no effects off I think 4 grams rue and like 20 grams of mimosa boiled to a tea and strained had soe golden glowand slight shimmers on thigns, but nothing notable really no psychedelia, but then the second time all I did was vomit, no effects at all, don't remember the dose of that trip but I think it was the same aoutnof harmalas, and maybe 30 grams mimosa in water. I also have reason to believe I did not get inner root bark as well, so the actual potency may have been the main issue in liquid but again this is why I prefer to freebase it and take it as powder. ALl around it seems more enjoyable, no taste to deal with less chance of nausea. And has worked to a perfect extent that I could hope for... where as liquid just doesn't seem to do it for me.

ALSO as another note someone mentioned gaba drugs such as alcohol, and benzos can SEVERLY downgrade the trip, so maybe you had a bad batch, aybe you had tolerance to other things, maybe you were on a benzo? THeres so many possibilitys, also some people just have a harder tie processing and metabolizing certain chems. If you go to the ER for an "OD" on a psyche or for a bad trip, they will give you IV benzos whether it be valium, xanax or whatever they deem fit, its basically to 1 ) keep you calm, and 2) to abort the trip, and I've been able to abort trips that were going astray by benzo use after aswell. I don't like ruining trips but this one inparticular came with a very bad body load, and the benzo was mainly to get rid of that, but instead aborted the enrire trip, rather than just dampen it literally from full blown psyche ode to baseline in 15-20 mins of ingestion of 1-2 mg etizolam.

One time I picked a handful of Psilocybe Semilanceata mushrooms to make a tea with two friends. On the way back I found a beautiful specimen of Amanita Muscaria. I Have been eating these for years as a culinary treat and I wanted to show my friends how to prepare it.

So while the psilo tea was brewing, I cooked the fly agaric in plenty of salt water, as usual. However, I let the mushroom cap float, so not all of the color would be flushed out. Obviously, neither would all of the active substances be flushed out. This I had done before and it is not a big deal, most of the psychoactives will be washed out. After the mushroom was drained from cooking water, it was gently fried.

One friend so much liked the taste of the fly agaric mushroom, that he ate more than half of the cap. Thereafter we drank the psilo tea. Me and the other friend had a mild trip, as the tea was not very strong. The guy who ate the most of the fly agaric reported the next day that he had had a beautifully intense trip, where he felt like in a fairy tale.

This suggests a synergetic effect between muscimol/ibotenic acid (GABA-ergic) and psilocybine (DMT-like).

I have not yet tried this myself, although I did once take a quarter dried fly agaric cap with valerian tea. It seems to have potentiated the valerian very strongly, as I suddenly fell fast asleep, to the surprise of a friend who was visiting me.

In my experience, 100 mg DMT fumarate should be more than enough for a brilliant experience. Even 50 mg is enough for many people.

When I started experimenting with pharmahuasca, I would preload with purified harmala alkaloids 30 minutes before ingesting DMT. This did not work optimally, with trips being rather mild. The improvement was to take DMT fumarate along with harmine/harmaline HCl to maximize the uptake of DMT. It seems that not taking the MAOI along with the DMT causes some DMT to be broken down in the gut and/or liver.

I found no difference in intensity between a solution and gelcapped pharmahuasca, apart from taste.

Based on my experiences and obeservations, I advise people to make proper extracts of both DMT and MAOI, weigh the doses and ingest together. For most people, 50 mg DMT and 200 mg harmalas should bring on a vivid experience of the DMT realm.

My current practice is to prepare gelcaps with 25 mg DMT fumarate and 125 mg harmaline/harmine HCl and ingest the caps with 30 minutes interval. That way, the peak of the effects is more spread out. Also, if two caps are not enough for the expected effects or one wants to prolong the experience, more caps can be taken. Some people seem to indeed need three or even four to match their expectations.

The effects of one capsule lasts about four hours, roughly the duration of the effects of harmala alkaloids. By taking a higher dose of harmalas, the effects are somewhat prolonged. I find that if I lie still after the harmalas have worn out, I can still maintain much of the dreamy state for many more hours.

Lastly, it is also very important to have a set and setting that allows for an intentful immersion into the DMT realms. First time I tried pharma, I cumulatively took 150 mg DMT with 250 mg harmalas (though not combined properly) and went cycling outside. The effects were very mild at best. Only later did I discover how overwhelming the experience can be, if it is allowed in.



AFAIK cooking ayahuasca tea from plants is an art as much as an extraction is. It is very easy to get it wrong if you do not know the proper techniques.

That is why I am in favor of extracting the active principles, because they can then be weighed. This makes the quality of the plant source less of a variable.

By ingesting raw plant materials, the stomach and gut do the extraction, this also introduces a variable (and possible nausea) that may negatively impact the result.

I'm speaking generally in terms of psych meds like tranquilizers, gabaminergics etc.

But more specifically in terms of GABA Analogs.

DMT is said to act on GABA receptors as well as fly agaric. But GABA analogs have a different activity at the same receptors.

I guess it could be compared to Salvia and Naltrexone in a way, both acting on opioid receptors.

I can vouch for the contradiction personally as i used a hefty dose of phenibut to derail a particularly strong Ayahuasca trip when a pressing issue interrupted the free time.

Another time I split 4 hits of good acid with a friend who was on some tranquilizer and he didn't notice a thing while for me the ground was flowing like a river.

Not that anyone with a history of psych difficulties should take psychedelics but I didnt think of that when i was 18.

Jonathan Ott has some stuff to say about Gabamimergics and DMT being contraindicated but I haven't heard it, another member referred to it.

If it doesn't help or ring true sorry I couldn't help but I haven't read what PubMed says about the role of GABA receptors and DMT yet.