Right now, all I have is a bunch of white sage and a bunch of syrian rue seeds. I didn't even know white sage could be smoked until I read a bunch of experiences about it.

So I'm wondering...what would happen if I took the rue and then smoked the sage? I've heard of people using rue with weed but not with sage. Do you think it would do anything? Thanks in advance.

White sage is for incense. It is burned on a coal for example. I've never heard someone talking about smoking it. For all i know, it's non psychoactive.

Indeed, white sage isn't psychoactive, but people do smoke it however...

To the OP: if you smoke this without infusing spice onto it, then all you could hope for, I think, is some effect from the harmala's in the rue...

powdered white sage goes very well in changa at around 10% of the total weight!

White sage is often smoked in Native American ceremonies, usually it is mixed with other sacred herbs and smoked in prayer. It does have a psychoactive effect ime; it's subtle but undeniable. To me feels almost like a clarifying effect or a centering of the senses somehow, I'd say it's almost a nootropic style effect. As mentioned previously it's an incredible changa additive and really enhances a blend immensely.

It's traditionally been used a tea for purifying the body as well as its most well-known use a smudge for energetic purification.

and yet, as someone who has smoked copious quantities of white sage, i deny psychoactive effects.

but then i don't feel anything from (high doses of) rue either, so clearly subtlety is lost on me

Sage has a high level of Thujone; I smoke a pinch of common Sage with herb(after reading a recommendation): it makes for a wonderful and dreamy blend.

According to a tiny amount of research, thujone is not found in salvia apiana (white sage) though it is present in salvia officinalis...
So flickedbio is right...

PLUR

"Indeed, white sage isn't psychoactive, but people do smoke it however..."

Yes it is. I have grown it, smoked it, and made resin extracts of it and smoked them also. It definitely is psychoactive and exactly what dreamer said.

The chemistry of this species of salvia is pretty complex.

Salvia is often used (in this context) to 'smudge' the ceremonial space to cleanse and positively charge the area. I love the smell of burnt sage, often add a pinch to Changa, and consider it an all round useful plant. Tastes great in cooking too

I used to think Salvia Divinorum was the only of the Salvia family to be psychoactive. Going to try some White Sage tea.

Have been using Officinalis for both tea to purify and incense to cleanse the room. In combination with Mugwort for both purposes as well.

If you're hanging out in some sacred space, and someone comes along with a smoldering stick of sage and smudges you, it is very likely you will experience the feeling of being "cleansed"...a distinct shift in consciousness which I would claim is evidence that the plant is "psycoactive". But ok, I believe our inquiry is about something different...so here it is:

Of course many of us have jumped at the opportunity to experiment with any plant even rumored to be "psycoactive"....so it was with me and sage...i tried smoking, tea and tincture in various doses, only to conclude that "it doesn't really do anything".

It wasn't until I got into brewing meade, (primarily medicinal and psychoactive brews, rooted in the Stephen Buhner tradition), that I discovered the secret:

Putting sage in the fermentation vessel *as it's fermenting* clearly brings about psychoactive effects that are not present in either tincture, tea or combined fractions.

For a long time I would make a batch of meade by creating an infusion of herbs, then add honey and yeast, creating a fine brew....tho one time I added a bunch of sage and mugwort to the carboy and left it there for 4 weeks as it fermented....I later served this brew at a party and just about everyone was coming up to me and asking what i had "dosed" them with

I have prepared many batches since then, sometimes using only sage, or only mugwort or only wormwood...the effects are all very similar...again...with tincture or tea...none of these plants seem "active" to me...but left to the wiles of the fermentation process we get a whole new product. I would love to hear if any chemistry-savvy folks out there have an explanation for how activity might be released through fermentation.

That's fascinating, I've never heard of anyone fermenting white sage. I'll give it a go.

I have tried smoking white sage before and the result was very subtle, but I was definitely slightly more relaxed afterward.

I recently made a batch of changa which I dubbed my "Salvia Special"

Salvia apiana
Salvia officinalis
Salvia divinorum 5x
1:1 ratio DMT
300mg harmalas extracted from rue

It's one of my best blends thus far.

I've smoked both Salvia apiana and Salvia officinalis and there is some psychoactive effect from both of these. It's nothing in your face and intense, but it's a general feeling of well-being and relaxation.

That's really interesting. Not that I really know the answer to your question, but perhaps a tincture like product results from fermenting. Thujone is said to be present in all three plants you named, and it is said to be most psychoactive as a tincture.

I am in the process of exploring Artemisia with rue, and so far they appear to be highly synergistic and bringing a significant deepening to the rue (with dmt or not).

hop biotransformation

Brewer's yeast has the ability to transform certain compounds. What we can say for sure so far is that they can transform essential oils in the hops and thus obtaining new compounds that have a different aroma to them. This is one way that beer brewer's use when making unique flavors in their highly hopped beers, many times IPA style beers. Also brewer's yeast excrete a lot of different enzymes that can work upon different compounds - another great is example is GAD enzyme (glutamate decarboxylase) which is important in working with Amanita muscaria mushroom. GAD can transform ibotenic acid into muscimol and thus create a much more desirable effect in the end product.

Thujone is a a terpene - as well as are essential oils. Thus I would not be surprised if it undergoes a change of a kind.

I think there is much to learn about yeast and other microorganisms that display fermentation and their effect on different compounds. Great that you brought up this white sage fermentation. In the last few months I'm paying much attention to this topic. I did start some experiments that are yet to be finished. You can look them up in the links below.

peganum harmala fermented tea

fermentation - amanita muscaria - IBO to MUS transformation

EDIT: If I recall correctly brewer's yeast can also transform some of the organic sulfides that are found in wort (wort is the liquid that becomes beer after fermentation with yeast).

There are many different terpenoids to be found in plants, which could be susceptible to transformation.