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L-dopa/tyrosine and MAOI dangers? Options
 
anrchy
#1 Posted : 6/23/2012 9:24:09 PM

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According to this website "Webmd you shouldn't take L-Dopa with maoi's. Further more you shouldn't take tyrosine with maoi's which I believe comes from macruna puriens. Can some one clarify on this for me? Cause I have on this forum where people are taking it with pharmahuasca or ayahuasca.
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corpus callosum
#2 Posted : 6/24/2012 10:05:52 AM

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WebMD is correct; taking levodopa with MAOIs runs the risk of a hypertensive crisis and levodopa should not be taken for at least 2 weeks after MAOIs; the risk of taking RIMAs (specifically moclobemide) with levodopa is one of increased side effects which include anorexia, nausea, vomiting, agitation, postural hypotension, tachycardia, arrythmias, hypomania, psychosis, depression, headache, flushing, gastrointestinal bleeding, itching, rashes, abnormal involuntary movements.

AFAIK, l-tyrosine taken with MAOIs renders it more likely to be a vasopressor ie cause an elevation in BP.


The thing to recognise about such advice is that some people may not suffer such adverse effects, but there is a significant likelihood of having such a response that it can only be considered wise to avoid such combinations.
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anrchy
#3 Posted : 6/24/2012 6:40:06 PM

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I don't seem to see anything on this website that states the dangers of taking these together. Seems to me that it should be posted as I say again people are mixing macruna with MAOI.
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endlessness
#4 Posted : 6/24/2012 6:59:14 PM

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anrchy
#5 Posted : 6/25/2012 6:43:49 AM

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endlessness wrote:


awesome glad I could help. Pleased
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Jees
#6 Posted : 7/25/2014 7:12:41 AM

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bump..

corpus callosum wrote:
...taking levodopa with MAOIs runs the risk of a hypertensive crisis and levodopa should not be taken for at least 2 weeks after MAOIs...
Never thought maoi could linger 2 weeks Shocked
Is there no different directive for irreversible and reversible maoi's?

Checking out different dealers on ebay and their advised dosages on mucuna / L-dopa , the range goes from:

50 - 150 mg L-dopa per day (usually those selling raw dried seed powder or extracts 15 to 40-50%)

til 500 - 1500 mg/day (usually those selling purified L-dopa in the 99% range of putity.)

This extreme range of dosages probably has it's effects on the safety time frame surrounding maoi? I have personal interest in a 50 - 100 mg L-dopa per day.

Is the safety-time before and after the maoi the same?
It would actually means no mucuna at all in my life style.

Thank you.
 
starway6
#7 Posted : 7/25/2014 8:56:07 PM

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anrchy wrote:
According to this website "Webmd you shouldn't take L-Dopa with maoi's. Further more you shouldn't take tyrosine with maoi's which I believe comes from macruna puriens. Can some one clarify on this for me? Cause I have on this forum where people are taking it with pharmahuasca or ayahuasca.


...[L Dopa].and ..[macruna puriens..]!
These are only [two] of the many leagle safe supliments we used as lucid dreaming aids...
But combining maio;s with them makes it more risky...
 
 
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