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I need an opinion on this medication please. Options
 
olympus mon
#1 Posted : 4/9/2012 11:09:38 PM

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I just got back from the doctor here in Peru. I asked for some ambien and valium for the 22 hour flight I have next week to England and then to the U.S and some long bus rides to Lima.

The doctor told me they don't have zolpidem aka ambien here but prescribed me something he said was similar. Midazolam. I am reading about this drug and I must be honest it sounds really heavy duty. Most notably that it is used to induce amnesia before traumatic medical procedures!Shocked Im just looking to catch some Z's on a plane not erase a chunk of time from my memeory.
So here is a copy paste from wikipedia. Could somebody with more knowledge than I please read it over and let me know if you think it just sounds worse than it is. there are many scientific terms that I dont understand relating to side effects and characteristics. I would really appreciate it.
Either way I feel if i do take it on the plane and 16 hour busride to the airport I should bio assay it in my hotel room first to make sure I dont do anything that could be a problem on a flight.
Thank you.
here is from Wiki

Midazolam[1] ( /mɪˈdæzəlæm/, marketed in English-speaking countries under the trade names Dormicum,[2] Hypnovel,[3] and Versed,[4] is a short-acting drug in the benzodiazepine class developed by Hoffmann-La Roche in the 1970s.[5] The drug is used for treatment of acute seizures, moderate to severe insomnia, and for inducing sedation and amnesia before medical procedures. It possesses profoundly potent anxiolytic, amnestic, hypnotic, anticonvulsant, skeletal muscle relaxant, and sedative properties.[6][7][8] Midazolam has a fast recovery time and is the most commonly used benzodiazepine as a premedication for sedation; less commonly it is used for induction and maintenance of anesthesia. Flumazenil, a benzodiazepine antagonist drug, can be used to treat an overdose of midazolam, as well as to reverse sedation.[7] However, flumazenil can trigger seizures in mixed overdoses and in benzodiazepine-dependent individuals, so is not used in most cases.[9][10]
Administration of midazolam by the intranasal or the buccal route (absorption via the gums and cheek) as an alternative to rectally administered diazepam is becoming increasingly popular for the emergency treatment of seizures in children.[11] Midazolam is also used for endoscopy[12] procedural sedation and sedation in intensive care.[13][14] The anterograde amnesia property of midazolam is useful for premedication before surgery to inhibit unpleasant memories.[15] Midazolam, like many other benzodiazepines, has a rapid onset of action, high effectiveness and low toxicity level. Drawbacks of midazolam include drug interactions, tolerance, and withdrawal syndrome, as well as adverse events including cognitive impairment and sedation.[15] Paradoxical effects occasionally occur, most commonly in children and the elderly,[15] particularly after intravenous administration.[16]
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Shiva H. Vishnu
#2 Posted : 4/9/2012 11:24:19 PM

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It's safe. start with the lowest dose if you're worried, but benzos all have pretty much the same profile. a high dose of any benzo can be amnesia inducing, but the doses prescribed are for anxiety and sleep disorders.
 
Bill Cipher
#3 Posted : 4/9/2012 11:27:33 PM

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I don't know about this, specifically, Oly, but valium is used as well to induce the same effect during surgeries. I think all benzodiazepines have this amnesiac effect to one degree or another.

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olympus mon
#4 Posted : 4/9/2012 11:30:49 PM

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Shiva H. Vishnu wrote:
It's safe. start with the lowest dose if you're worried, but benzos all have pretty much the same profile. a high dose of any benzo can be amnesia inducing, but the doses prescribed are for anxiety and sleep disorders.

Thank you Shiva, so the amnesia effect is from high doses if I understand you correctly?
I was given 15mg pills which is listed as common doseage for healthy adults so Im happy that I dont have to worry about this. The pills were incredibly expensive!!! i was prescribed 20 but could only afford 6. Hope their fun for how much they cost, Laughing

Thank you for your help.
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Shiva H. Vishnu
#5 Posted : 4/9/2012 11:35:48 PM

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i don't know the relative potency of this particular benzodiazapine. the highest dosage of valium available is typically 10mg, an equivalent dose of xanax being 1mg, and i believe the same is true for klonopin. it really doesn't matter if you're going to be sitting in an airplane seat, though. they will all make you feel nice and dreamy and relaxed until you ultimately fall asleep.
 
Bill Cipher
#6 Posted : 4/9/2012 11:36:24 PM

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Just don't mix with alcohol. I've lost entire days mixing valium and alcohol (long ago...).
 
olympus mon
#7 Posted : 4/9/2012 11:41:28 PM

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Uncle Knucles wrote:
Just don't mix with alcohol. I've lost entire days mixing valium and alcohol (long ago...).

What and miss out on the fun of drinking on benzo's. Art you clearly dont understand the loadie that dwels within me, Laughing

J/k Ill be careful, thanks guys for the help.
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Shiva H. Vishnu
#8 Posted : 4/9/2012 11:42:09 PM

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Uncle Knucles wrote:
Just don't mix with alcohol. I've lost entire days mixing valium and alcohol (long ago...).


yes. it was irresponsible for me to forget to mention this. do not be tempted to drink alcohol. all bets are off if you make this combo.
 
Mister_Niles
#9 Posted : 4/10/2012 12:44:16 AM

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Just an FYI. Street name for midazolam around here is Dazzle. Based on that name, I'd say use it with caution. I remember taking some halcion (triazolam) back in the 80's... oh wait, I don't remember. At all.
I take about 1.25 mgs of Valium daily. Weaning down slowly from 5mg for a back problem. Valium is my favorite benzo other than tranxene. Before the valium prescription I only took them maybe once a year and I've never had a problem with them. They have great utility though.
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corpus callosum
#10 Posted : 4/10/2012 11:15:14 AM

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Good stuff is Midazolam!

The only issue, Oly, is that it has a half-life of about 4 hours which makes it less ideal than say diazepam/lorazepam/nitrazepam for keeping one asleep.

Ive never tried the tablets but I once came across a 10mg/2ml amp of it; this taken IV produced the most impressive amnesia Ive ever had.Since Roche stopped making Rohypnol this has been used for nefarious purposes as it has a similar effect when taken with alcohol.
I am paranoid of my brain. It thinks all the time, even when I'm asleep. My thoughts assail me. Murderous lechers they are. Thought is the assassin of thought. Like a man stabbing himself with one hand while the other hand tries to stop the blade. Like an explosion that destroys the detonator. I am paranoid of my brain. It makes me unsettled and ill at ease. Makes me chase my tail, freezes my eyes and shuts me down. Watches me. Eats my head. It destroys me.

 
Macre
#11 Posted : 4/10/2012 11:48:37 AM

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Uncle Knucles wrote:
Just don't mix with alcohol. I've lost entire days mixing valium and alcohol (long ago...).


Yeah I third this. The most unsettling thing is, it's not just a foggy memory, it's a total, utter and complete blank. For me too, this was long long ago, it's part of my past I'm happy to forget (pun intended Very happy).

Peace

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