^^^^^^^
I don't know exactly, but oral is like 3-5 hours basically and sublingual/smoked is much less, like an hour or two maybe.
Tramadol's SNRI effects persist for around 12 hours, and there will be excess serotonin and norepinephrine in the brain for a longer period than that. I would wait a few days after tramadol to use any RIMA's.
HOWEVER! I once (very stupidly) took some harmel tea (with mushrooms) a few hours after taking 100 mg tramadol, and didn't die or experience any adverse effects to speak of. Don't take that as a confirmation of the safety of the combination. I was being an idiot.
بسم الله الرحمن الرحيم
Fairly responsible Kratom user.
"whenever he drank ayahuasca, he had such beautiful visions that he used to put his hands over his eyes for fear somebody might steal them."
in between the grinding-brakes of a train crash while aluminum-foil robots make obnoxious sex noises on a static-filled walkie-talkie radio.