Harmala alkaloids can attenuate SOME of the features of withdrawal in morphine-habituated rats when withdrawal is precipitated by naloxone but Im not sure that they would do much to make the rattle significantly easier in humans.
To the OP- I think you misunderstand where your real difficulties lie in the process of getting clean.I may be wrong ,but the impression I get from your post is that you havent been free of some kind of opioid stimulation for longer than a few days at most, and your present state, whilst not the 'narcotic nightmare' you describe, is still slavery with a more civilized face on it.
As most who have had a liking for poppy juice et al would agree, the withdrawal period is exceedingly hard to endure but most would have done it more times than they care to recall.The real battle which defeats most users repeatedly is the staying off of these chemicals.
The hardest way to quit is a straight cold turkey with no chemical help at all but this, if done successfully, leaves the most enduring desire to never treat opiates in the way youve thus far done.It takes some mental preparation to get your head in the right place for coping with whats to come (rattle, life after the rattle) and if you really do wish to leave these drugs behind, it is not impossible.But anything to take the edge off the process of withdrawing is certainly welcome.IMO the following are incredibly useful things to have close to hand:
1.Benzodiazepines- they have some handy anxiolytic and anti-nausea properties, but, IME, you are not going to get a decent few hours sleep no matter what doses you take.Be wary, as these too can be habit-forming if use goes on beyond the first week.
2.Pregabalin or Gabapentin- excellent for the restless legs.
3.Other opioids- for example, if you are quitting bupe/heroin/oxy, having some codeine or dihydrocodeine can really help if used in fairly small doses at days 2-4; the overwhelming feeling of emptyness is definitely smoothed out a little by these without retarding the process of withdrawal significantly.Again, best used for a couple of days at the peak of the nastiness.
5.Lofexidine and clonidine-the hot and cold flushes resulting in part from cental increased noradrenergic activity are eased by these, but some find they make them too dizzy to even stand up.Others are less impressed with these drugs but they do have some effect.
6.Loperamide for the diarrhoea-note codeine and dihydrocodeine will also do this nicely.
7.Tramadol- whilst relatively useless as a replacement for strong mu agonists, it can really help ameliorate the process of withdrawal.
8.Ibuprofen- Im not impressed with this, but some feel it can help the febrile feelings.
The above meds can really make withdrawal not too taxing at all, when combined properly but this requires a thorough knowledge of the different interactions between the many possible combinations and means alot more than just taking some of this and some of that.Alot of these meds when combined give a more than additive effect and this can be hazardous with respect to ending up aspirating on your own vomit if your drowsy enough to not wake up in time.
The mental attitude is key here.For those in the 'narcotic nightmare' it usually means changing your whole life in some fundamental ways.If youve managed to stabilise and change your life by going onto some kind of maintenance therapy then you should find the process not quite as demanding, as the crux of the work has already been done.But its important to be be prepared for a minimum of some weeks to quite possibly many months of whats known as PAWS (Post Acute Withdrawal Syndrome) where general apathy, lassitude and depression just persist.Some users of buprenorphine feel that the PAWS with this compound is really quite long-lasting.
Lastly, no post on this topic would be complete without mentioning ibogaine.I have no experience personally of using this for the purpose of withdrawal, but I think if you want 'insights' into your motivations for the life youve lived so far, then this would by all accounts be the weapon of choice.
I am paranoid of my brain. It thinks all the time, even when I'm asleep. My thoughts assail me. Murderous lechers they are. Thought is the assassin of thought. Like a man stabbing himself with one hand while the other hand tries to stop the blade. Like an explosion that destroys the detonator. I am paranoid of my brain. It makes me unsettled and ill at ease. Makes me chase my tail, freezes my eyes and shuts me down. Watches me. Eats my head. It destroys me.