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Alkaloid Analytical Information Options
 
kinkyking
#1 Posted : 4/26/2011 3:27:57 PM

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Where is the place to look up for the specific properties of any alkaloid for matters like pH tolerance and such?
For example when someone wants to know the maximum low and high pH range an specific survives in, where's/what's that scientific reference he shall look up to?

Or other information like: What happens when an alkaloid gets 'destroyed' in unsuitable heat, or pH, or other environmental factors. What it turns into exactly?
 

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endlessness
#2 Posted : 4/26/2011 3:34:23 PM

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You can start with something like the WIKI: https://wiki.dmt-nexus.m..._and_Physical_Properties

What do you mean "specific survives in"? Some alkaloids will not be sensitive to degradation with high or low pH, others might. Or maybe you mean the pKa, which says in a given pH how much of a certain alkaloid will be in salt or freebase (and therefore soluble in some or another solvent) ? In that case most of that info will be in the WIKI. If more people have more information on interesting alkaloids, feel free to add there Very happy

Other resources (that we try to include in the WIKI) is merck index, pubchem, and also information from suppliers like sigma aldrich and etc (for example they might say solubility or storage conditions/sensitivities, etc)
 
kinkyking
#3 Posted : 4/26/2011 3:47:15 PM

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By survival pH range, I mean the pH range in which a given alkaloid (Mescaline for example) can be fine (Salt or freebase) and not get destroyed (And what does it turn into when it gets destroyed?)

I named mescaline just for example, it might not be sensitive to pH at all (I don't know yet) or it may destroy, let's say in pH higher than 10 and lower than 2 (Again, only hypothesizing).

Generally, any given properties of any given alkaloid. where's the source for that kind of knowledge?
 
endlessness
#4 Posted : 4/26/2011 3:52:37 PM

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Did you read the above link? Mescaline has no known pH sensitivity, and neither do most of the alkaloids we usually talk about here, with the exception of psilocybin (which dephosphorilates to active psilocin in acidic conditions), and yuremamine iirc.
 
kinkyking
#5 Posted : 4/26/2011 4:36:50 PM

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I've read the link above before, I'm speaking generally.
 
kinkyking
#6 Posted : 4/26/2011 4:40:07 PM

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pubchem seems very useful, thanks.
 
Jin
#7 Posted : 4/26/2011 5:31:28 PM

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kinkyking wrote:
I've read the link above before, I'm speaking generally.


can swim ask whether you're doin an extraction ? , for if so then you'll have to be more specific wth the particular issue so the members can help you with that
otherwise if its just curiosity or research on the subject that got you asking these questions then proceed as you may
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benzyme
#8 Posted : 4/26/2011 6:27:47 PM

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