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Physical effects of too much dmt? Options
 
soulfood
#21 Posted : 4/30/2010 2:07:45 AM

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Metta wrote:
You guys do know you can straight up die right?

Like if you smoke too much dmt, you will stop from breathing, and it only takes a few minutes of not breathing to have permanent brain damage and then death.

I didn't read this whole thread but even if I did, this point needs to be emphasized heavily. The difference between medicine and poison is the dose.


You can't physically smoke that much though.

Thats the main plus side of this method of administration.

You will not get that far.

IVing is a different story.
 

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Oncewas
#22 Posted : 4/30/2010 2:19:27 AM
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let me show you an excerpt of tihkal on 5-meo. I know this isn't dmt however this is important to notate. I've heard of stories of similar happening with freebase nn-dmt.

Quote:

(with an unknown but large amount, smoked) I observed the subject pass very quickly into an almost coma-like state. Within seconds his face became purple and his breathing stopped. I pounded his chest, and breathed for him, and he seemed to emerge in consciousness, with the comment, "This is absolute ecstasy." He stopped breathing a second time, and both heart massage and mouth-to-mouth resuscitation was provided. Again, he recovered and managed to maintain a continuing consciousness and achieve a partial recovery. In the awake condition he was increasingly lucid, but on closing his eyes he became possessed with, what he called, "The energy of terror." He could not sleep, as upon closing his eyes he felt threatened in a way he could not tolerate. Three days later, medical intervention with antipsychotic medication was provided, which allowed the recovery of an acceptable behavior pattern in a few more days.
 
jamie
#23 Posted : 4/30/2010 2:25:57 AM

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fnog9 wrote:
Hello! I am planning on taking a monumental oral dose of white spice. Other than possibly passing out and barfing, what are some other risks of taking too much?

I heard that if you take too much, you develop some kind of alergic reaction or something? Something to do with too much serotonin the system? And this causes a swelling of air ways and a lot of mucous production or something. Can someone clarify this, or what really happens? Also, what's the remedy if this does happen?

Also, I've heard no one's ever died from taking too much dmt. Well what if someone did like a gram or two of it? What would happen to them physically?


Wow..you must be new, becasue this is one of the stupidest posts I have seen in a long time..I wonder if your even old enough to be here? This is like just unbelievable..fresh of the school bus or what? Imnot even going to warn you since there are enough people before me doing that. If you still take a dose like that you deserve what you get..do you want to ask questions abotu sticking your finger in the light socket or portable radios in the bathtub as well?
Long live the unwoke.
 
soulfood
#24 Posted : 4/30/2010 2:35:15 AM

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Ah shit...

I didn't read the OP..

fuck...

start off small dude.

Learn to drive before you hit the speedway. You'll know when you're going fast enough.
 
greymatter
#25 Posted : 4/30/2010 2:44:15 AM

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i also like to travel, but man are you fuking nuts! i can personally confirm the stop breathing thing when some fucknut on phish lot sold my friend a gram of "dmt" that turned out to be dyed 5meo...i ended up giving him cpr ...fortunatly he survived but didnt remember a thing
 
shoe
#26 Posted : 4/30/2010 2:49:46 AM

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The Traveler wrote:
What is happening lately with with all those people who want to use a monumental or heroic (yuck) dose? Did you ever slowly tried to increase the dosage? Believe me, when you take too high a dose two things can happen: or you get a horror journey or you just black out and cannot recall much of it.

I can understand that when you slowly increase the dosage that you finally reach your monumental/heroic dose so you know your limit. But without those intermediate dosages how can you know that those dosages aren't your sweet spot?

If you want to increase the oral dosage then I want to advice you to use DMT-fumarate. DMT-fumarate is absorbed much faster in your body as compared to freebase, this way you will get a much less stretched increase of DMT in your bloodstream and your peak will be reached faster. For me an oral dose of 100mg freebase was my sweet spot, when I took 100mg DMT-fumarate it was way too much!

So I state it again: slowly increase your dosage to find your sweet spot, if you grow into a grandpa within a second you miss all the childhood/teenager/adult parts of your life and that would be a big shame.


Kind regards,

The Traveler



Give this guy a break. Have you all forgotten what Terrence McKenna said? you SHOULD be taking a large dose of DMT. Just one, large dose. very infrequently, maybe once or twice a year. Thats the methodology here, seriously.

Although personally, I don't want him to freak out and have a brain aneurism or something. So, probably best to take soulfoods advice and get a little experience first hehe
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ragabr
#27 Posted : 4/30/2010 2:55:41 AM

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Ummm, much respect for McKenna and everything, but why should we just take his word as gospel? Thought he always pointed out that you could test everything that he said, regarding meeting the UFO's and whatnot. SWIM has had so much personal growth ever since she began actively engaging the Spice and the community here at the Nexus. One large dose once or twice a year would not have done this. Any dose much beyond her breakthrough level has ended up a waste, only instilling anxiety symptoms in the body that she later had to work through.
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ms_manic_minxx
#28 Posted : 4/30/2010 2:55:43 AM

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Say it takes 50mgs of spice to blast off. That's way too much for me. Say it takes 10 ounces of alcohol to get rip-roaring drunk.

What would happen if you smoked 2 grams of DMT?

What would happen if you pounded 400 shots of vodka in an hour?

Do you see the SHEER ABSURDITY of the question?
Some things will come easy, some will be a test
 
corpus callosum
#29 Posted : 4/30/2010 8:24:53 AM

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William Blake said "The road of excess leads to the palaces of wisdom".

I dunno whether or not you have ever had an unbearably heavy psychedelic experience or not, but your desire to take monumental doses makes me suspect you havent.I may be wrong.

Respect yourself and the spice.

Analyse why you wish for such an experience...... and do yourself and other fans of hyperspace a favour and wise up.

No-one here needs the potential hassles that can come from the ill-advised excesses of just one person.

The psychiatric ward or graveyard are not the palaces of wisdom you want to end up in!

There are plenty of seasoned explorers here at the Nexus and you would be well advised to listen to their wise words.Ignore them at your own cost.

As all hardy venturers know, its a fairly fine line between a useful instructive experience and one which overwhelms and crushes, with little benefit to be derived.And think about what youve said-'a gram or two'-that should strike anyone with a modicum of intellect thats thats an absurd dosage escalation.

Be wise, go slow and recognise that 'blazing' such a trail is something that Nexus elders would be reluctant to do, for reasons that are patently obvious to most of the people here.

Take it EEEAASSY!

I am paranoid of my brain. It thinks all the time, even when I'm asleep. My thoughts assail me. Murderous lechers they are. Thought is the assassin of thought. Like a man stabbing himself with one hand while the other hand tries to stop the blade. Like an explosion that destroys the detonator. I am paranoid of my brain. It makes me unsettled and ill at ease. Makes me chase my tail, freezes my eyes and shuts me down. Watches me. Eats my head. It destroys me.

 
vovin
#30 Posted : 4/30/2010 10:37:28 AM

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I have taken some pretty extreme dosages of DMT and I am still around. I didnt have a way to measure milligrams but I know it was about all a human could get in. After 40-50 trips you get it down. Nothing really bad happened due to dosage and there is a little cap on just how high you can get. So the excess might only extend the trip for a little bit longer that is all.
If you don't sin, Jesus died for nothing.
 
endlessness
#31 Posted : 4/30/2010 10:46:50 AM

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notice he was talking about ORAL dosage, not smoked dosage.. With smoked dosage there is a certain limit where you just cannot physically smoke anymore. In fact, I pretty much try to get to this limit every time I breakthrough. I fill my vaporgenie with changa, maybe 100mg total dmt, and just keep hitting with full dedication, even if the whole world has already transformed into a fractal rubiks cube, as long as I still have control of my hands I keep on taking more puffs. The vaporgenie being so efficient, I can never finish all what I loaded in the genie, there's always a lot left for a second or even third launch

with oral dosage, its a completely different thing.. the OP was talking about taking one or two grams (!!!) orally, which is just absurd, reckless, and shows either he is not saying the truth (maybe thinking hypothetically, or joking, or whatever) or that he really doesnt understand the possible consequences of his actions. Either way, its pretty obvious he should not do that
 
Blackstatis
#32 Posted : 4/30/2010 11:18:33 AM

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i've looked it up before and the LD-50 is 4 grams. theres no way at all you can smoke that much and if you eat 4 grams of spice... well thats just ridiculous.
 
Infundibulum
#33 Posted : 4/30/2010 12:10:36 PM

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Blackstatis wrote:
i've looked it up before and the LD-50 is 14 grams. theres no way at all you can smoke that much and if you eat 14 grams of spice... well thats just ridiculous.

Is it 14 grams with or without MAOI? Could you also check this thing for us please? Also please reference species. People rarely report LD-50 for humans; we're not in the 3rd reich.

dmt may as well be orally active (without MAOI) at 13 grams and lethal at 14.


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The Traveler
#34 Posted : 4/30/2010 1:17:44 PM

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shoe wrote:
The Traveler wrote:
...



Give this guy a break. Have you all forgotten what Terrence McKenna said? you SHOULD be taking a large dose of DMT. Just one, large dose. very infrequently, maybe once or twice a year. Thats the methodology here, seriously.

Although personally, I don't want him to freak out and have a brain aneurism or something. So, probably best to take soulfoods advice and get a little experience first hehe


And what would you think McKenna would mean with a large dose? Of course I can never be 100% sure about this but I'm very confident that he didn't mean 1 or 2 GRAMS. If 80mg orally is a normal dose then 150mg would be a rather LARGE dose don't you think?


Kind regards,

The Traveler


p.s. I see a lot of swearing and shouting here. Please refrain from this people! We aren't in some stock market. Very happy
 
endlessness
#35 Posted : 4/30/2010 1:34:25 PM

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shoe wrote:



Give this guy a break. Have you all forgotten what Terrence McKenna said? you SHOULD be taking a large dose of DMT. Just one, large dose. very infrequently, maybe once or twice a year. Thats the methodology here, seriously.

Although personally, I don't want him to freak out and have a brain aneurism or something. So, probably best to take soulfoods advice and get a little experience first hehe



if you read the original post you'll see your advice is quite irresponsible IMO.. First of all, just because Mckenna says something doesnt mean one should follow it or believe or take literally. Critical thinking first and foremost!

Secondly, Mckenna doesnt seem to have experimented with oral pure dmt, when he talked about large doses he talked about 5g dried mushrooms or vaporized dmt.

Third, we're not just talking high dose, the OP was talking about ingesting 1 - 2 grams of dmt with MAOI !! Thats most definitely NOT the methodology here.

So I dont think we should "give this guy a break" if you mean that we should stop giving him constructive criticism, our honest opinion and be working for safety, but I do agree if you mean, as trav said, that people should stop shouting and name-calling at each other.
 
Apoc
#36 Posted : 5/2/2010 6:39:49 AM

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People, people!!! I was just looking for information. Basically, I was wondering if dmt is similar to lsd, as I have read reports of people taking humongeous amounts of lsd and suffering no apparent physical effects. I was wondering dmt was similar.

From what I've gathered, basically, no that is not the case. People seem to agree that it is very bad to take such large doses orally, yet surprisingly, I still haven't seen any real evidence of this. I was looking for links to studies, or at least anecdotal reports. But all I've seen so far is, "that's stupid", and reports of people who stop breathing while smoking 5meo. Well, tell me why it's stupid, specifically. Does it give you a heart attack? Does it stop your heart? Does it poison your blood? Does it give you cancer? liver damage?

As I said, yes I was planning on taking a high dose, but my dosage was going to be influenced by the responses I got, so as to gague just how physically dangerous the substance is. I was looking for the information, I don't see why that's stupid. Also had no intention of taking a gram or two. Was just wondering if it had ever been done, and what would happen. I figured there have probably been studies done on it, since there have been sutdies done on virtually everything. But if there haven't been, I guess there haven't been.

Thanks for the LD50 report. That is useful.
 
polytrip
#37 Posted : 5/2/2010 1:52:01 PM
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The liontamer movie i posted was showing you exactly why it is undesireable to be 'adventurous' in this way: the guy wants to be a liontamer because he thinks it's an exiting life but when he's shown a picture of a lion he's struck by the terror of fear.

The same thing is true for taking what some people call 'heroic' doses of psychedelics in the sense that it seems fun talking about it. But if you don't know what you're dealing with and if you even have no idea what to expect you can only end up freaking yourself out completely.

I know exactly what s going to happen when you take a tenfold dose of oral DMT (the dosage for oral DMT seem to differ from person to person). You will already be experiencing a sense of pure terror and panick like you never had in your entire life and you can't even imagine right now, at the beginning when it's coming up. It will start at the moment you're realizing that you've taken way, way more than you can handle, that it's already way, way more than you can handle and you're not even there yet. And it's getting heavier and heavier and heavyer by the second. And this phase where it's getting heavier and heavier will last for minutes.

If you're lucky you will pass out. If you're unlucky.....you'll end up in a looniehouse where you stay for the rest of your life or you will hurt yourself seriously.

People here say 'that's stupid' because they know what DMT is and what it is capable of.

DMT can make you experience bliss like you can't even imagine, but we all respect the spice because it does so by taking us up to the edge of the abys and no sane person wants to go further.

From experience i can say that with a dose that could make me trip 5 times i'm already starting to lose it. Maybe some people can handle more.

But everybody who ever went as far as experiencing what 'starting to lose it' is like will say: that's as far as i'm willing to go and no further, because that will only bring you pure insanity.

I went as far as looking into the abys only, getting a glimpse of what pure insanmity is like.
Many of us have.

And THAT's the reason that people here say 'that's stupid'. Because just a glimpse of it is enough to know that you don't wanna go there.

And you're talking of a dose that might exceed the stage of pure insanity and terror by who knows how many times. 50 mg is enough to make some people have a full breakthrough with oral DMT, while some need maybe 200 mg. 2 grams may be 10 breakthrough doses for you, or it may be 40, but it's way over the edge of the cliff anyway.
 
ismokecrystals
#38 Posted : 5/2/2010 7:26:58 PM

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Jesus you guys act like it's going to fuck him up forever.

If he wants to do it, he will do it no matter what. If you do do it, have a sitter who knows CPR on standby. I agree with the McKenna quote, most of my learning experiences were when I took WAY too much and I lost consciousness and forgot it all. However, the best part about this is piecing everything back together. You can learn much much more when you are sober than under the effect of any drug.

Large doses of DMT transport you to a place and you don't have any breadcrumbs to get back. If you can mentally hold it together, fucking take a huge dose. Just keep in mind the risk that you are taking. a 1 gram oral dose is ~10-20x a normal dose. Do you think you can handle TEN TIMES the intensity of a smoked DMT trip? If you think you can you probably can.

You're venturing into largely unknown territory here- not many have done what you want to do, probably for good reason.

My best life experience by far was under the influence of 10 hits of needlepoint LSD, 3.5g p. cubensis, 200mg PURE MDMA, >5g heady-ass ganja and at LEAST .3g DMT.
I can tell you that had I done this alone, I would have died either through hurting myself or doing something stupid. However, I had great sitters that made sure I was OK at all times. I can't put that experience into words but it fully changed who I am today because I wanted it to. I got exactly what I wanted out of that trip and felt ZERO ill effects.

Make sure that you have a plant before you embark on this journey or you will just get lost.
 
polytrip
#39 Posted : 5/2/2010 8:31:42 PM
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ismokecrystals wrote:
Jesus you guys act like it's going to fuck him up forever.

Do you think you can handle TEN TIMES the intensity of a smoked DMT trip? If you think you can you probably can.


I have to disagree with this.

1-it might actually fuck him up forever...like you said, doses this large are unknown territory. DMT might be neurotoxic at this level, we don't know. But assuming this is safe is stupid since most neurotransmitters will cause some kind of problem if they exceed certain levels, so you must be assuming that DMT is fundamentally different from almost all others substances in this respect.

2-if you think you can handle you probably can....
We don't know the guy, but considering his question and intention to take this much DMT we must assume that he at the very least has very little experience with DMT and certainly not with large doses.

If you ask such a question you must absolutely have no idea what you're doing.
Any idea that he can handle this must be based on ignorance or overconfidence.

He probably thinks that the worst thing that can happen is that you see scary stuff, and that he'll be able to tell himself that it's not real and just a hallucination if that happens.
He clearly doesn't realize that the rabithole goes way deeper than just seeing funny shit.

You could start to feel that you're possesed by some demon and that you cannot tell the difference anymore between your own thoughts and the demons thoughts, for instance.
I think everybody experienced with large doses of DMT (within the normal range of) will agree that such a thing could be a very modest scenario and that the terror can easily be much worse than that.
 
soulfood
#40 Posted : 5/2/2010 9:01:10 PM

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I've had an accidendental high dose I estimated to be around 4 times my usual range of 40-80mg's.

It was very much a "wake me up when this is over" kind of thing. But that was not anywhere near the dosages discussed in this thread. I don't think anything worthwhile can happen with these amounts.

Also I'd imagine it would be very difficult to consume that amount and keep it held in for long enough without ejecting it. But this should not be taken as a safeguard against an OD.

I think you'd probably just get to the stage wher it becomes so much to handle that you will just black out. Then when you wake up you will be really confused and feel all kinds of rough.
 
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