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Previously Undescribed alkaloids and anti-tumor activity of P. Harmala Options
 
Woolmer
#1 Posted : 8/7/2022 3:07:33 PM

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https://www.researchgate...from-Peganum-harmala.pdf

While the paper is rather focused on the anti-tumour capabilities of P. Harmala with indeed very interesting results, it also lists 6 undescribed alkaloids of P. harmala, as well as 6 alkaloids that were not known to occur in the genus of peganum. To note they used aerial parts of the plant.

Quote:
In our previous investigation on the seeds and roots of P. harmala, a series of antitumor alkaloids with novel scaffolds such as pegaharmines A-D, peganumine A, and pegaharmols A-B were found (Wang et al., 2016, 2017; Li et al., 2020). HPLC analysis on the total alkaloids from the aerial parts, seeds and roots of P. harmala revealed the presence of different constituents. Thus, our investigation on the alkaloids of the aerial parts of P. harmala led to the isolation of 20 compounds including six previously undescribed ones.

 

Live plants. Sustainable, ethically sourced, native American owned.
 
murklan
#2 Posted : 8/7/2022 10:01:27 PM

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Good finding!
I don't understand much of the paper, but I really hope that it leads to further studies of this fascinating plant.
Thank you.
 
Jees
#3 Posted : 8/8/2022 2:33:51 PM

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Thumbs up Woolmer.
I'm too green to understand all, but the result counts.
 
dithyramb
#4 Posted : 8/8/2022 4:44:09 PM

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The aerial parts are very active. It was too strong and serious for me and I couldn't get myself to try drinking light on top of it. The seeds appear recreational in comparison... Thank you for sharing.
The consciousness of plants is a constant source of information for medicine, alimentation, and art, and an example of the intelligence and creative imagination of nature. Much of my education I owe to the intelligence of these great teachers. Thus I consider myself to be the “representative” of plants, and for this reason I assert that if they cut down the trees and burn what’s left of the rainforests, it is the same as burning a whole library of books without ever having read them.

~ Pablo Amaringo
 
Woolmer
#5 Posted : 8/8/2022 7:01:38 PM

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Interesting account dithyramb.

Would be curious to hear more accounts, as the aerial alkaloids are clearly different to the seeds.

Quote:
By analyzing the structural characteristics of all the separated products, the main alkaloids from the aerial parts of P. harmala were found to be quinoline- and quinazoline-type, which were significantly different from the alkaloids reported in seeds and roots.
 
dithyramb
#6 Posted : 8/8/2022 7:31:38 PM

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Yes it is very interesting. Even with such a difference in alkaloids, the visuals were the same as seeds. Triangular patterns and pyramids are a very common theme in my allied strain of rue.
The consciousness of plants is a constant source of information for medicine, alimentation, and art, and an example of the intelligence and creative imagination of nature. Much of my education I owe to the intelligence of these great teachers. Thus I consider myself to be the “representative” of plants, and for this reason I assert that if they cut down the trees and burn what’s left of the rainforests, it is the same as burning a whole library of books without ever having read them.

~ Pablo Amaringo
 
 
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