Just wondering about this alkaloid that sometimes is mentioned in the recipes with/without dmt: as far I understand is not a MAOI itself but is often used in combination with harmalas.. cannot get what kind of beneficials it has and if it has some effects if taken itself

as you may see in the New insights into the chemical composition of ayahuasca thread, theoretically concentrated banistropsis cappi brews if you don't drink the sediment which is usually the idea actually has more THH than harmine and relatively little harmaline, as opposed to most pharmahuasca which is made from paganum harmala seeds which means it usually has a 60% to 40% harmaline:harmine with very little THH content, as to the difference of the effects induced by these chemically different analogues IME harmine+THH lasts longer, does not cause nausea, has an awakening effect as opposed to dream/sleep inducing, far clearer and energetic compared to harmaline+harmine which has a shorter duration, does cause nausea and loss of motor control, has a dream inducing effect and is much less defined and relaxing

keep in mind that is the experience of just taking harmala alkaloids with no DMT or other substances for me, IMHO it can be better for beginners (by that i mean everyone) to begin with the harmaline+harmine combination since it leaves less freedom to maneuver for the experient, or in other words operates more closely to metabolism of nervous cells making it less of an intrusive manipulation of neurochemistry

Thank you very much for your deep explanation!
Usually I take a tea with 3grams of rue seeds (1 hour boiling) and small amount of vaped DMT; if I would add the THH what would be the procedure/dosage?

Its MAOI activity is very weak indeed. It also has very weak activity as an SSRI.

Edit: I had suggested a thread about the effects of pure THH, but I found out the product was possibly not pure THH.

if you really want my opinion i'd say consider taking up a meditation practice and research meditative states from original sources and try things like iboga and cactus and harmalas without the DMT to be able to put your own situation in scope better before taking up the use of vapurhuasca or aya/pharma

otherwise i think you should start incrementally and find your own way if you choose to go forward

Without taking anything away from your experience with THH...
Since it acts as an (S)SRI, THH doesn't block serotonin: it inhibits serotonin reuptake thereby increasing its concentration in the synaptic cleft. Its activity as an SRI is very weak though, otherwise it would give problems since it is often taken with MAOIs.
LSD, mescaline and mushrooms don't block serotonin either, instead being agonists of serotonin receptors.

What would a good dose of Caapi vine be for...

1. A gentle experience to "say hello", be functional immediately and 100% functional a few hours later.

2. A "trip", touching most of the bases, but still enabling "normality" in a reasonable amount of time.

I am an older gentleman (66, I hate to belabor that, but it's a factor) who is exploring manageable experiences while his ladyfriend is at work (I'm retired).
She is aware, and not against this, so no deception. she is just still working for now. Possibly she will join me at a later date.

Hmmmm. The Liftmode stuff is bogus, right?

Perhaps not bogus, but not entirely pure due to green glow under blacklight. However, it's been speculated that even a miniscule amount of harmine or harmaline in the THH may cause a green glow in a majority THH sample.

One love

Note: Let's try to avoid mention of suppliers as harmalas are illegal in some parts of the world.

Thanks for the answer and sorry about that. Should I delete or edit?

Of course

And no worries at all. I'll take care of it if something needs to be changed. It's on the border. But you're all good and no harm done

One love

Thanks for all these awesome answers! in particular @ava69, it seems this substance can give me the experience I'm looking for!
Which dosage of THH should I take for my vaporhuasca sessions? should I REPLACE the rue seed, take less rue seed (usually 3grams) or just add 150/300mg of THH?

I will! Thank you so much to take the time to get me such detailed explanation!

Peace&Love

Have you any thoughts on making a changa blend with harmine + THH? considering different proportions.

thinking 50% Peganum extract (harmine:harmline) and 50 % THH freebase
then another batch with just harmine/THH

overall harmala content around 20-25%

also - if i went the HARMINE + THH route, should the amounts be bigger, as both are weaker MAOIs than harmaline?