Hi Eels (etc),
Peyote are my favorite cactus, by far! I've never eaten any of mine, and I have only been keeping them (as a friend [some may call "pet"]) for about 5 years.
From seed - if grown naturally, you won't be eating them any time soon, lol. Super slow growers from the roots. Some people graft them to some stock in order to accelerate growth. Personally? I'm a roots-type grower. I don't care about the slow growth, as I don't intend to eat them. They are certainly worth the grow, though. Fun little critters.
For mescaline - as wolf said, many people just choose the trichocereus instead. They are faster growing, and generally available in most countries. If you don't intend to eat right away, even better. Live cuttings are pretty easy to find and grow.
Growing is the gift that keeps giving.
Take care!
ACY
O, LSD, right. Dose will be based heavily on the individual user and their body/tolerance. At some point, I feel that it becomes easier to "experience" effects that are representative of a higher dose, even when the dose is lower.
Frequency plays a role. The general observation is that frequent use builds tolerance. So, someone may take 100 ug, then 200 ug, then 500 ug, and up - all in a short time frame. Due to frequent use, maybe the 500 doesn't "feel" too much different than the 200. If that person takes a break for a while, and doses at 200 ug, it might feel like what could be interpolated as 350 ug. That's because they had already built a tolerance from the 100 ug, prior to the 200 & 500 ug.
For me, if I am going to take LSD, then I'd prefer to just take 250 ug. It's been a few years since my last experience with LSD. I've still got some - but eventually hit the point of: oh, i'm good on this for a while. After an irresponsibly (IMO) high dose of >1 mg, I decided that I'd found my personal threshold. 250 ug will be just fine, if I ever take LSD again.... (I'd like to think so, but I'm most interested in phenethylamines, currently.)
Mescaline, no matter what plant makes it, is one of my favorites. For oral consumption, likely THE favorite.
Sometimes it's good for a change. Other times it isn't.