Mescaline itself is actually one of the most researched psychedelics yet, and it also has an incredible history of human use
In 1886, Louis lewin published the first methodical analysis of the Peyote cactus, I'm not sure why erowid failed to start the timeline here, regardless, the erowid timeline is below
Quote:
Nov 23, 1897 Mescaline is first isolated and identified by German chemist Arthur Heffter.
1919 Mescaline is first synthesized by Ernst Spath. 1
1927 An extensive study of mescaline's effects was published in Der Meskalinrausch (The Mescaline High).
Oct 1945 US Navy Technical Mission reports on mescaline experiments at the Nazi Dachau concentration camp.
1947 U.S. Navy initiates mescaline studies under the auspices of 'Project Chatter'. 2
1952 Dr. Humphry Osmond begins working with hallucinogens at a hospital in Saskatchewan, looking at the similarity between mescaline and the adrenaline molecule
-erowid
Plus researchers such as Lewin, Arthur Heffter, Albert Hoffman, and modern researchers such as Alexander shulgin and David E. Nichols have put in a good deal of research regarding this compound...organizations such as
www.maps.org also hold a wealth of information regarding mescaline
Quote:Mescaline has always been the central standard against which all other compounds are viewed. Even the United States Chemical Warfare group, in their human studies of a number of substituted phenethylamines, used mescaline as the reference material for both quantitative and qualitative comparisons. The Edgewood Arsenal code number for it was EA-1306. All psychedelics are given properties that are something like "twice the potency of mescaline" or "twice as long-lived as mescaline." This simple drug is truly the central prototype against which everything else is measured. The earliest studies with the "psychotomimetic amphetamines" had quantitative psychological numbers attached that read as "mescaline units." Mescaline was cast in concrete as being active at the 3.75 mg/kg level. That means for a 80 kilogram person (a 170 pound person) a dose of 300 milligrams. If a new compound proved to be active at 30 milligrams, there was a M.U. level of 10 put into the published literature. The behavioral biologists were happy, because now they had numbers to represent psychological properties. But in truth, none of this represented the magic of this material, the nature of the experience itself. formal ; shulgin ".
There is art work at Chavín de Huantar in the northern highlands of Peru depicting San Pedro caucus which dates from 1400-400 BC, San Pedro cacti are also a decorative motif in later Peruvian ceramic traditions, such as the Salinar style (c. 400-200 BC), the Nasca urns (c. 100 BC-AD 700), and others.
Peyote as well:
Quote:he religious use peyote is very ancient. One cache of dried peyote found in a Texas cave, has been dated at approximately 7000 years old -erowid
Below is an example of such ancient peyote
Quote: Peyote alkaloids: identification in a prehistoric specimen of lophophora from coahuila, Mexico
Abstract
Mescaline, anhalonine, lophophorine, pellotine, and anhalonidine have been identified in alkaloid extracts of a prehistoric specimen of Lophophora from a burial cave in west central Coahuila, Mexico. The specimen is associated with radiocarbon dates of A.D. 810 to 1070 and is one of the oldest materials ever submitted to alkaloid analysis.
http://www.ncbi.nlm.nih.gov/pubmed/17796678 The key would be finding holes in the currant knowledge, and placing your research there, because while a good deal is already known, there are still many things we have yet to learn...
If you do manage to preform some research more power to you, there actually is research to be done.
Some research: (though it may not touch on the topics of research which you listed)
http://www.ncbi.nlm.nih.gov/pubmed/600028http://www.ncbi.nlm.nih.gov/pubmed/5511715http://www.ncbi.nlm.nih.gov/pubmed/991995http://www.ncbi.nlm.nih.gov/pubmed/5788766http://www.ncbi.nlm.nih....pmc/articles/PMC2763256/http://www.ncbi.nlm.nih.gov/pubmed/3358338http://www.ncbi.nlm.nih.gov/pubmed/6682439http://www.ncbi.nlm.nih.gov/pubmed/20170392https://www.researchgate...d_in_biological_matriceshttps://www.researchgate...nce_to_shamanic_practice(You may be really interested in this one!)
https://www.researchgate...hora-williamsii-The-mainhttps://www.researchgate...-the-excessive-amount-ofhttp://ebookinga.com/pdf/pihkal-mescalinehttp://abcnews.go.com/bl...ld-lsd-treat-alcoholism/(Mentions mescaline to treat addiction)
http://news.discovery.co...s-depression-122301.html(Mentions mescaline and depression)
Quote:Mescaline has a wide array of suggested medical usage, including treatment of alcoholism[11] and depression.[12] However, its status as a Schedule I controlled substance in the Convention on Psychotropic Substances limits availability of the drug to researchers. Because of this, very few studies concerning mescaline's activity and potential therapeutic effects in humans have been conducted since the early 1970s. -Wikipedia
So it seems medical study is needed....
This is just the tip of the ice-berg, there is actually much more research out there, much is better than some of the research posted, the links above are all fairly modern, which is why they were chosen.
-eg