So, I was wondering. Is it safe for someone who is taking fluvoxomine (ssri) cousin of prozac to toke DMT? Just smoke, not ingest.

http://en.wikipedia.org/wiki/Fluvoxamine
Fluvoxamine (brand names: Faverin, Fevarin, Floxyfral, Luvox) is a medication which functions as a selective serotonin reuptake inhibitor (SSRI) and σ1 receptor agonist. Fluvoxamine is used primarily for the treatment of obsessive-compulsive disorder (OCD),[3] and is also used to treat major depressive disorder (MDD), and anxiety disorders such as panic disorder and posttraumatic stress disorder (PTSD).[4] Fluvoxamine CR (controlled release) is approved to treat social anxiety disorder.[5]

The FDA has added a black box warning for this drug in reference to increased risks of suicidal thinking and behavior in young adults and children.


Interactions

Fluvoxamine inhibits the following cytochrome P450 enzymes:[20][21][22][23][24][25][26][27]

CYP1A2 (strongly) which metabolizes agomelatine, amitriptyline, caffeine, clomipramine, clozapine, duloxetine, haloperidol, imipramine, phenacetin, tacrine, tamoxifen, theophylline, olanzapine, etc.
CYP3A4 (weakly) which metabolizes alprazolam, aripiprazole, clozapine, haloperidol, quetiapine, ziprasidone, etc.
CYP2D6 (weakly) which metabolizes aripiprazole, chlorpromazine, clozapine, codeine, fluoxetine, haloperidol, olanzapine, oxycodone, paroxetine, perphenazine, pethidine, risperidone, sertraline, thioridazine, zuclopenthixol, etc.
CYP2C9 (moderately) which metabolizes Non-steroidal anti-inflammatory drugs, phenytoin, sulfonylureas, etc.
CYP2C19 (strongly) which metabolizes clonazepam, diazepam, phenytoin, etc.
CYP2B6 (weakly) which metabolizes bupropion, cyclophosphamide, sertraline, tamoxifen, valproate, etc.

By so doing fluvoxamine can increase serum concentration of the substrates of the aforementioned enzymes

I don't feel comfortable giving you a thumbs up to mix these.