hello

this question is more directed toward the harmalas, but in general its for everything in pharamhuasca.

would would be the physcial repercussions of taking pharma on a weekly or bi weekly basis?

many of the groups who perform regular rituals do it every two weeks, but the reason why remain a mystery to me (short of limited supplies and an attempt to gather people together for a communal experience).

there is another thread on here about aya, not pharma, being hard on your liver, you would have to change your diet and be more aware of what your eating, you could not regularly purge without suffering a hernia, the harmalas could build up in your system and it would fundamentally alter your brain chemistry, not to mention the question of if you would emotionally be up to it.

but from a purely physical standpoint, looking at damage done not from excessive doses but from regular controlled doses, what kid of risks would be involved with taking pharma on a regular basis.

and the second question is how often would you advise would be safe? obviously once every two weeks would be ok if the communes are an example, but even then has their been any study on the physiological effects?

and before anyone asks, this is hypothetical, i have had such a scare of the stuff as of late that you cant even pull the jars out without having my heart rate jump, and its been mostly centered around a concern around my long term health, even taking it once every few months.

so in short what kind of physical repercussions to your long term health could result from taking pharma 1-3 times a week if it were possible/emotionally able to do so?

thank you.

If by pharma you mean using literally a pharmaceutical like maclobemide(sp?)ad an MAOI, I think that would potentially be alot worse for you, as pharmaceuticals from my understanding have a longer half life I could be wrong on this, but then again I feel anything pharmaceutical would almost certainly be worse on you regarding these substances.

TOXSIN pharmahuasca is simply extracted dmt and extraacted harmala alkaloids, nothing to do with phaarmaceuticals. Although moclobemide could be used.

Why is it called Pharma then? Because its easier to encapsulate? I know the few times I actually experienced visions off aya I used 2G syrian rue split into 3 caps 700MG in 2 and 600MG in the 3rd with 100MG DMT freebase in there as well so total of 2100MG material in 3 pills eating the 2 rue caps first waiting 10-15 mins between them with the rue/DMT cap last and I had a great time EVERY time lol, brews never seems visionary for me, would what I did there though be considered pharma than?

Yes that is pharma that you had. I suppose because the ingredients in pharma are in pure chemical form that's why it's called pharma. I assume

I don't think there's a single answer for the OP's question. It likely varies from person to person. I would probably lose my mind if I tripped on anything weekly or bi-weekly, but every two weeks seems to be ok.

I say, just go with your intuition. If you pay attention to how you are feeling and thinking, you should know well before anything serious happens whether or not you should slow down or take a break.

A potential risk could be dramatic weightloss if one's ritual for pharma includes fasting beforehand, not eating during the long experience and potentially vomiting as well. Along with the purge also comes the risk of hernia or pulling something as they can be quite violent.

^ Yeah weight loss is one thing, especially since harmalas seem to inhibit appetite the morning after as well. Although when i was taking pharma/aya once a week i never really noticed much of a difference in my weight. A lot of the time i would eat a small meal 3 or 4 hours before dosing.

Anonenium, i think the risks are depend on the individual and things like dosage. They're more psychological risks, not physical risks (unless of course you mix it with something like ssri's or mdma..then your asking for trouble). Just go with the flow and what you feel is best for you personally at this point in your life, and you should be fine

I have taken ayahuasca or pharma weekly for about 3 years.

I definatly dont think it suppresses my appetite. Sometimes I pretty much need to eat after to recover all my energy. Ayahuasca can tire you out if you take heavy doses and have to endure it all night long.

well thkan you to everyone for your opinions and thank you jamie for telling me there are people who can do it.

i dont know if i would ever be able to bring myself to that point, but i would like to, its just particularity for the harmala i dont know what kind of effect regular use would have but given the fact that its used as a antidepressant and is given to some people daily (but in the 20mg or less range) it cant have that bad of a profile.

but i wanted to have another opinion before i considered it, and maybe some day i will feel able to bring myself to it.

thank you to everyone for weighing in.

morning anonenium,

here is a study on consistent Aya use, I know its not exactly the same as Pharma but its worth a read.

http://www.plosone.org/a...1%2Fjournal.pone.0042421