the problem with desomorphine is it is made with otc adulterated chems / products.
they react codine with some form of eye drops which i believe contain thionyl chloride along with some nasty catalytic reduction with some method of demethylation using adulterated otc products then they end up with desomorphine + pollutants.
its probably the crap in the final product that rots the flesh rather than the synthetic opioid itself.
i believe if they hit the vein its ok, its when they miss it causes the problems and rots the flesh. in one video i saw some of the addicts had lost limbs!
i could be wrong about the exact procedure but this is to the best of my knowledge from watching youtube videos and reading an article a while ago.
hope this helps
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