I've brewed my first batch of aya and was intending to drink it this weekend. Last night I did a last run through of RIMA interactions, and turns out what I thought was a straight synthetic opiate (Tramadol) actually has seratonin and norepinephrine reuptake inhibiting actions as well. Wikipedia says 14 days between uses of Tramadol and MAOIs, but I wanted a second opinion. I've taken 150 or 200 mg a day without break for a good year, and the half life is 9 hours, so carrying 25-30 mg forward each day, I've got a good bit built up.

Anyone know about Kratom interactions? I don't take it regularly and have only taken a few ever, but I have some and would like to know if I should consider it contraindicted.

Thank you!

I recently took myself off Tramadol as well I was taking for a pinched nerve. I tapered down to 50mg a day and was on the medication for 2 months this time when I stopped cold turkey. I hate this shitty med for the side effects and the problems it caused me in life and in my relationships. It also seemed to drastically reduce the effects of dmt. The minor pain relief I got from this med was in no way worth all the bullshit. Tramadol is the devil of meds IMO.

It only took a 5 days for it to feel fully out of my system. I did a LOT of reading about tramadol and maois and what I concluded was they are not dangerous with RIMA's which is what channga, ayahausca, rue, ext are the danger are irreversible types of MAOI.

Ive never had any signs or problems with mixing tramdol and RIMA's other than that it has negative effects on the experience but no health concerns. I have even drank ayahuasca while on Tramadol which I dont recommend but had zero health issues. The experience was dark and un intelligible.

The amount of time you were on Tramdol is quite a while, from everything i have read Id say 2 weeks is sufficient but longer is better. Think twice before you get involved with kratom IMO. It can be a wonderful useful plant and can be a shitty ass addiction. I dodnt know the counter effects of kratom and entheos sorry.

I appreciate the response, and I'm glad to hear someone with significant aya exerience knows about this.

I totally agree with your tramadol analysis. Funny thing is, as soon as the vine arrived, the (overseas) pharmacy I got them from shut down. Coincidental timing, if I do say so...

I'd second what olympus mon just said, it's one bad ass drug, and you will probably have some godwaful withdrawal from it as well which can last up to 2 weeks anyway. I wouldn't try Aya .untill that withdrawal was over, otherwise you could be setting yourself up for one hell of a dark trip.

I've heard reports that Kratom can lessen the withdrawal from tram. So that might help. It'll be "easier" to get off the Kratom after that.

Be well.