I'm going to dose tomorrow. I have some 10x Rue seed extract. It's my understanding that for a 300lb person, I should be dosing about .3-.5mg for it's reversible maoi effects. I think I'm going to start with .4.

10 minutes later I'll be dosing 50mg of dmt freebase, then 10 minutes later another 50mg. All of these will be in lemon juice or orange juice.

I expect this will be a moderate, but controllable experience? I've smoked as much as 80mg doses of DMT (accidental overdose) and normally breakthrough on 40mg or so. I've read a lot in the pharma section and elsewhere. Does anyone have any tips for me? I will be dosing on the floor, with every blanket I can find. I plan to sit still in the sunlit room (blinds closed) with no music/noise. I am attempting (not demanding! ) a religious experience

I'm going to give this a shot, and I apologize in advance if anyone upon reading this misconstrues this as irresponsible advice: Go big if this is your first oral dose. Oral DMT is intimidating, even at fairly low doses. In my personal experience, I consumed a tea from 15 grams of mhrb my first time and I haven't gone that deep since. I don't know if this it out of fear or out reverence for DMT or both, but it is what it is. There's always the chance that if you start conservatively and work your way it might be a much longer road to a peak religious experience. When it comes to DMT, fear of the "known" trumps the fear of the unknown, and prior to your first oral dose is the only time you will have no frame of reference for the intensity of the experience. If nothing else, go forward with confidence and remember that everything will be fine no matter what dose you choose.

Hi bignoggin,

I myself have not yet tried oral DMT, but did already some research on the topic here on DMT-Nexus. What I learned was that oral DMT dosage (or tolerance to it) for some reasons varies rather greatly - probably due to personal metabolism, bodymass, body´s reaction to MAOIs etc...

From my readings of other Nexian´s reports and thoughts, I personally would rather start lower than 100mgs for the first time...

Anyway, keep us informed how your journey went.

You know...my comments may not be liked either but I couldn't have said it better myself. This is great advice. not everyone will be ready to take it but its spot on IMO.

I hold back telling people this but its true, if your trying to know the mind of god then dabbling and testing the waters isn't going to impress you. Be smart about it but I truly feel that the confident and committed explorer often finds what they are seeking and the meek often fall short time and time again. There is something very special and un duplicated about your first time with any psych. You only have one shot at your first time and often they are the most memorable and the ones we chase again our whole lives.

There is a bravery and stamina that only a first timer has. Some people may understand what I am saying here.

To address the OP. 100mg isnt a small dose. For some it may be threshold others the sweet spot but I doubt 100mg would be too much for anyone that is mentally ready for an oral dmt experience. Take that for what its worth.

"Olympus mon", "Un-known-ome" (and other defenders of "heroic doses" ) I think I understand the points you are making. I translated it as "go deep if you (think you) are ready for it"... I have no problem with that.

In the last Erowid newsletter, I found some interesting data on a scientific psilocybin research. The guys from Johns Hopkins found out - I will make it brief here - that "starting low and slowly making one´s way up" produces more "positive" evaluation of the psilocybin experience than "jumping deep" right from the beginning (check it out here, if you were interested: http://www.erowid.org/ch...silocybin_article3.shtml)

I don´t want to extrapolate their findings from Psilocybin to oral DMT, but do you consider that these effects would be too different for Mushrooms and oral DMT?

(I am not arguing with more experienced travellers here, I am just trying to learn more before launching my first oral DMT travel )

Cool beans thanks for that Im def interested in reading this article.
My thoughts are this, I do see some differences between mushrooms and things like aya or even mushrooms and rue. Those also takes on a aya like dream state. I can see why starting slow but working up is good with mushrooms. I guess i just feel that low dose oral dmt and even some medium dose arent really that exciting or helpful for me. Ive had a lot of duds and Id way rather have a rough ride than sit in the parking lot. You have to understand I dont believe in bad trips. The best thing that has happened to me was getting my ass kicked repeatedly with ayahausca so take what I say with a grain of salt.

You know at the end of the day its more important to do what you are comfortable with rather than do what anyone advises even if that person has a good amount of experience. Its your body and your mind. There is nothing wrong with starting low. The op mentioned wanting a spiritual experience. i think that is why some of us are advising to go for it.

always remember....

"Fortune favours the BRAVE"

Thanks for the advice. I think 100mg split into in 2 doses will be a good combo.

I just took .1mg of 10x syrian rue extract to see what it's effect on BP/etc would be. At T+10m I'm going to take .4, then T+15m, 50mg DMT, then T+25m another 50mg of DMT with .1mg of rue.

Here's to the elves!

In my experience when you are looking or seeking a more manageable experience, it ends up blowing my socks off. Just be warned! You're still taking oral DMT and anything can happen.

"I just took .1mg of 10x syrian rue extract"

thats nowhere near an active dose..do you mean .1g of 10x? That would be more in line with an oral dose..keep in mind that IME the "10x" rue extract I had was not really 10x stronger than plain rue at all..it was probly more like 5x in reality.

I don't know if you read the whole sentence but I explained myself I think.

T+0m .1mg 10x rue (testing for B.P. and allergic effects)'
T+10m .4mg 10x rue
T+20m 50mg n-n-DMT
T+30m 50mg n-n-DMT + .1mg 10x rue
T+1:15m 50mg n-n-DMT + .3 10x rue

I barely had threshold effects. All was taken in lemon water.
I took 2 minor hits of smoked n-n-DMT and had some minor CEV's, but I couldn't get the effects to stay.

Basically a boring morning spent talking to a tape recorder. I put away my rue and n-n-dmt. I will attempt oral again if I get some good feedback.

I am 330lbs... Perhaps my large stomach has a lot of MAO flying around and I just need more rue?

What you are saying here is that you took what is advertised as equivalent to 1mg of rue and then 10 minutes later you took the equivalent of 4mg of rue. 10x *.1mg = 1mg 10x *.4mg = 4mg. That's pretty much nothing...unless that's not actually the dose you took.

Also, I would advise extracting your own harmalas so that you know what you are dealing with. It seems to me that people have more issues with these __x extracts than anyone does with alkaloids they extract.

I read the whole sentence..what I dont think you understand is that, like snozz said you claim to have taken only .9mg of a 10x rue extract..which is equal to 9mg of rue! 9mg of pure harmalas wold not even come close to doing anything, so 9mg of rue def wont do anything. This is why I asked if you mean took .1g or the 10x and not .1mg..the difference between mg's and g's is huge. What you claim to have ingested is not even a fraction of the dose required. you say you took .9mg alltogether of 10xrue..so that is 9mg of rue..well for inhibition you are going to need at least 1000mg of rue! It is no wonder that you experienced nothing other than probly some minor placebo.

My normal harmala dosage for rue extract would be between 100 and 300mg, depending on how long I want the journey to be. My weight is about 180lbs.

If your rue is really 10x then I would advice you to take about 30mg of it. If it is more like 5x as jamie stated then you will need about 60mg.

Pharmahuasca is pretty much a game of finding out what works for you. Also with pharmahuasca other things affect the dosage needed, like when was your last meal, etc.

Though for the next time I would go for the right harmala dosage as I stated before.

Good luck!


Kind regards,

The Traveler

I'm terribly sorry. I was unsober when I wrote those posts. It was, in fact grams, not milligrams. Originally I was going to put 100mg, 300mg, 100mg, 300mg.

Everything I read varies wildly on total rue I needed to eat and the time frame relative to the DMT dose. Everything from immediately (ala ayahuaska) to 20 minutes after.

Now that my screw up/typo is known, is the consensus still that I just needed to eat more rue?

The DMT is potent, but I'm unsure of the chemical makeup. Cut me a little slack, I'm pretty new. My first extraction won't be for a while because I think I am taking a long break from DMT.

so, was your total amount of harmala 800mg???

did you get noticeable harmala effects?

I got very little effects what so ever. I'm not sure what to do now. Most people seem to come into a dose/schedule they are comfortable with after much playing around.

Some seem to suggest that I should have taken the dmt sooner because I was on an empty stomach. Some say I need more rue extract. I guess next time I'll try 1g of 10x rue and 100mg of DMT just 1 minute later.