I'm willing to take pharmahuasca hence few questions.

I tried to take Syrian Rue with shrooms few years ago. I took the Rue powder and I felt some head buzz and nausea. As soon as I swallowed mushrooms afterwards I puked and it was all over. Is there a way to avoid nausea while taking Syrian Rue? Are alkaloid extracts from the Rue less prone to it?

The next thing I'm trying to grasp is how different ways of DMT administration interact with MAOIs. Say I take the Rue beforehand, then DMT. What will be the difference between taking it orally, through vaporising or intramuscularly? Do different ways affect the profoundness and duration of the trip?

Hello zigizigi, and welcome.
To answer your question ingestion rue seeds as is (simply crush and wash down) is the surest way to get nausea.
A tea from 3 grams would be less nauseous but the more nausea free method is to extract it's alcaloids, namely harmine and harmaline, via manske.
Manske is a method of extraction with use salt and vinegar a few times to purify the alcaloids and get rid of all those nauseous compound in rue.

So yeah if you didn't already, have a look at the extractions on wiki page, my favorite so far has been the harmalas extraction and separation guide (you don't need to separate them, the mix is fine for pharmahuasca or vaping).

https://wiki.dmt-nexus.m...ion_and_Separation_Guide


And good luck with your pharmahuasca, it's a wonderful ROA when it comes to n,n-DMT, you're rigth to prepair well for a comfortable journey, the magic is awesome there !

I've always just made rue tea.

Spend a lot of time reading threads in the ayahuasca and pharmahausa and also the harmalas sub-forums. Thats where I learnt the wisdom of brewing the rue tea and letting it sit for days in the fridge before decanting it (thanks jamie). A lot of solids will precipitate and you don't need to drink that stuff. A lot of people will prefer extracted harmalas however--I've never tried, so I can't say.

I have finally tried rue + smoked DMT mix. I made tea out of 0.3g of 10x Syrian rue extract and only felt some slight headache at the level of placebo effect. I inhaled 25mg of vaporized DMT freebase off a bulb 25 min after. Damn it's harsh!

So all I had was a short yet rich tryptamine high with beautiful visuals that lasted about 10 min and it was all over. I read that such combo yields 1-2 hours long trip but my experience was more like pure DMT smoking.

Is something wrong with the commercial rue extract I got? Maybe it's not as strong as advertised?

What does the rue extract tea taste like? Mine was pretty much mild, not bitter and nasty at all. On the other hand the tea I made off normal ground rue seeds few years ago was a yellow extremely bitter tasting nauseous fluid, really hard to swallow and keep in stomach.

"Off a bulb"? You must mean a lightbulb vape....that's not a good method. Properly vaped spice after oral harmalas is more like 10-30 minutes, not 2 hours.

What's wrong about lightbulb as a vaporizer and what's better than that?

They burn DMT, no one uses them.

There are many options, I compiled some of them in the link in my signature.