Hello

So SWIM just got some grams of yopo (a. peregrina) and of epena (v. theiodora). They are both made mixed with the ashes of Elizabetha Princeps tree.

SWIM will save some for using, as they are straight from yanomami, but its too much, so SWIM was thinking of extracting some..

So considering the yopo has 5-HO-DMT and epena has 5-MEO-DMT, can SWIM make an A/B with defatting on both of them and will the final product be bufotenine and 5-meo?

SWIM will try to get acetone to make the other acetone bufo tek instead, but it seems its controlled in his country... So would this work as a normal A/B, using glacial acetic acid, NaOH and naphtha as the non-polar solvent?

thanks

Not for Yopo. Freebase bufotenine is very polar and quite insoluble in Naphtha. You'll need a semi-polar solvent like DCM, ethyl acetate, chloroform, etc.

It should work for epena. From what I recall, 5-MeO-DMT is soluble in naphtha.

thanks a lot

anybody else can confirm 5-meo is soluble in naphtha? will attempt that this weekend..

You think a defat is necessary? SWIM is a bit affraid of emulsions in the defat step

btw, you think 5-meo can be freeze precipitated in naphtha, or only evapped?

and what about the pka of 5-meo, any info on that?