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Cebil Options
 
Noman
#1 Posted : 12/19/2006 8:16:23 AM

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Someone I know just recieved a bunch of Cebil and wants to try some extraction experiments. Ideas?
 

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The Traveler
#2 Posted : 12/19/2006 10:25:15 PM

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Here are links I found after some searching: http://en.wikipedia.org/wiki/Vilca http://forums.lycaeum.or...mp;f=2&t=001548 Interesting qoutes: [quote:96c2979fe7]ISOLATION AND PURIFICATION OF BUFOTENINE FREE-BASE Coarse-ground powder of 125g of seeds of A. colubrina var. Cebil was stirred twice for eight hours in 500 ml of 96% ethanol 1% tartaric acid, the combined filtrates concentrated to 150 ml and diluted with 200 ml water in a separatory-funnel, causing precipitation of considerable fat. The pH was adjusted to 3-4 with concentrated hydrochloric acid, and the solution defatted by shaking six times with chloroform, which was set aside. The defatted extract was basified to pH 8-9 with ammonium hydroxide, then again extracted eight times with 200 ml chloroform; the combined chloroform extracts were concentrated to a foamy, yellowish oil that dissolved completely in 50 ml hot ethyl acetate, then concentrated to 15 ml and refrigerated overnight. In the morning there were a brace of minuscule rosettes of dark-brownish crystals growing at the base of the flask, which was alternated between periods under refrigeration and standing unstoppered at room temperature during 48 hours, leading to the formation of large masses (some greater than 1cm) of dark-brownish, prismatic crystals. The mother-liquor was decanted and the crystalline mass rinsed with cold ethyl acetate dried over magnesium sulfate, then dried under reduced pressure to yield 4.1 g of large, free-flowing, sparkling brownish crystals. These were twice recrystallized from dry ethyl acetate, yielding 3.87 g of off-white bufotenine free-base crystals (3. 10%), m.p. 125-126 C. Despite loss of chromophores on recrystallizations, the melting point remained 124-126. Six reports of isolated bufotenine free-base, from Amanita citrina (Schaef.) Gray (Agaricaceae) (Wieland & Motzel 1953) and Anadenanthera species (Rendn 1984; lacobucci & Rdveda 1964; Pachter, Zacharias & Ribeiro 1959; Alvares Pereira 1957; Stromberg 1954-yields reported were from 0.94-7.4% for A. peregrina to 0.5-2.1 % for A. colubrina), disclosed two crystalline isoforms from ethyl acetate, one melting from [123-]124-126[-129] C, the other 146-147[-150] C. Two reports of synthetic material disclosed a third isoform, with melting points of 138-140 C (Stoll et al. 1955); and again 146-147 C (Speeter & Anthony 1954). In all cases involving the lower-melting-point isoforms, repeated purification did not alter the melting point, although Iacobucci and Rdveda (1964), upon seeding a recrystallization-solution of their lower melting point isoform (123-124 C) with crystals having m.p. 146-147 C, got only crystals of the latter type, which operation was not reversible. By manipulating conditions of recrystallization from ethyl acetate, I was able to generate crystals melting at 145-147 C, and confirmed Iacobucci and RtIveda's observation. DMT free-base from hexane likewise exists as at least three isoforms, melting points from 44-74 C having been reported, and Fish, Johnson and Horning (1956) replicated the irreversible transformation of a lower-melting-point isoform (47-49 C) into a higher-melting-point isoform (71-73 C). Identity and purity of isolated bufotenine were verified by mass-spectral analysis and thin-layer chromatographic comparison with an authentic sample in several solvent systems. [/quote:96c2979fe7] [quote:96c2979fe7]You can forget about the DMT and 5-MeO-DMT. If they are present, you won't feel them. The only thing you really feel is the bufotenine.[/quote:96c2979fe7] [quote:96c2979fe7] EXPERIMENTAL: Isolation of Bufotenine. - Piptadenia (Anadenanthera) peregrina seeds, 891 grams, secured from Las Mesas, Puerto Rico, were ground in a Waring blendor and extracted twice with 4 litres of 1% ethanolic tartaric acid solution for 2 hours at 55F8. The resulting 8 litre of solution was filtered, concentrated to a volume of 1 liter and diluted with 2.5 liters of water. It was acidified with 200 ml of 2N hydrochloric acid. The solution was filtered and extracted six times with 200 ml portions of chloroform. The chloroform solution was discarded. The acid solution was neutralized with solid sodium carbonate. This was divided into two parts and each part was extracted seven times with 200 ml portions of chloroform. The combined chloroform solutions were extracted with 2N hydrochloric acid. This acid solution was made basic with solid sodium carbonate and the base was re-extracted with chloroform. After drying, the solvent was removed to provide 20.95 grams (2.45%) of mixed organic bases. A crude alkaloid fraction, 10.11 grams, was subjected to chromatographic separation on alumina (Merck Reagent). An ethyl acetate fraction contained 0.12 gram of a brown oil. The bufotenine fraction was eluted with 3:1 ethyl acetate-ethanol to give 7.66 grams of material. Several recrystallizations from ethyl acetate gave 4.09 grams (40% of the alkaloid fraction), melting point 146F8-147F8. Bufotenine represents 0.94% of the Piptadenia seed. The material remaining on the column was eluted with ethanol to give 2.31 grams of residue.[/quote:96c2979fe7]
 
Noman
#3 Posted : 12/20/2006 6:50:14 AM

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Very happy What a wanker am I that you have to find me a thread on the very forum that I moderate!? Embarrased That procedure looks very interesting. I'm also thinking about things I've hear about converting bufo into DMT or 5MEO.
 
The Traveler
#4 Posted : 12/20/2006 10:19:39 AM

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[quote:348ae9acd5="Noman"]Very happy What a wanker am I that you have to find me a thread on the very forum that I moderate!? Embarrased [/quote:348ae9acd5] Very happy I was unaware of you being an Uberator on that forum. I just googled to it. Do these coincidences keep popping up? To your defence; it was in the archive section of that forum. Cool
 
blacksheep
#5 Posted : 12/20/2006 5:18:45 PM
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Nah, he's a wanker... I was under the impression that bufotine was completley undesireable, as in pure toxic effects without the psychedelic overtones?
!!SNAP~KRACKLE~POP!!
 
Noman
#6 Posted : 12/20/2006 8:24:49 PM

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Well, the jury's still out on whether bufo is completely undesirable though I'm not really after it. I'm more interested in converting it through heat treatment or enzymatically. Of course if I could just isolate it, then it stands to reason that the residue would contain the other alks if present.
 
Taliesin the Alchemist
#7 Posted : 3/6/2007 12:10:06 AM
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[quote:f99d245884="Noman"]Well, the jury's still out on whether bufo is completely undesirable though I'm not really after it. I'm more interested in converting it through heat treatment or enzymatically. Of course if I could just isolate it, then it stands to reason that the residue would contain the other alks if present.[/quote:f99d245884] I've had a few experiences with yopo cebil. I wouldn't say that it's (bufotenin) undesirable! It's pretty intense though, you do get pressure in your head and something of a sinus infection for a few days after insulfation. But I had visuals every time and an OOBE too, on one occasion! It has some value as an enthoegen. Don't rule it out. It's not for the faint of heart though! yopo was a little frightening to me every time I used it! I'm still interested in yopo, although next time I think I will experiment with yopo vIlca (peregrina) as opposed to cebil.
[img:f1b61c1c99]http://209.235.244.14/www.visioncrystal.com/images/gal-11753.jpg[/img:f1b61c1c99] Psychedelics are probably responsible for every aspect of human evolution apart from the decline in body hair. ~Terence McKenna
 
 
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