downwardsfromzero wrote:Bancopuma wrote:Serotonin doesn't pass the blood-brain barrier, [...]
Hey doubledog, growing Pan cyans is definitely a little more fiddly than growing Pan cyans, with tweaks to substrate and fruiting conditions required, but the basic process is the same, and growing them certainly shouldn't be considered as very difficult.
Would ingested serotonin contribute to nausea, though? Kind of contra to the increased smoothness idea, I know - I suppose it depends on the relative k
ĭs of psilocin and serotonin at the 5HT3 receptor (or whichever).
And presumably you mean "... more fiddly than growing
natalensis... "?
Given the amount of serotonin receptors in the gut, definitely feasible for some kind of interaction on that front. Ha yes and you're right, that's indeed what I meant - have edited for clarity, thanks
Quote:Perhaps it does not need to cross the blood brain barrier to have an effect?
Possibly, but I'm not sure through what mechanism it would have a noticeable effect without impacting the serotoninergic system that the psilocybin is also working on. If there is serotonin knocking around in the fungus, by extension that means there will also be serotonin precursor compounds present which
could be bioactive to some degree, so I don't think their potential influence should be overlooked even if the serotonon itself might not be exerting an influence.