Hi guys!
http://www.ijstr.org/fin...Antiseptic-Potential.pdf

I could see the reasoning behind using a soxhlet for the extraction of polyphenols/phenolic compounds, but there's no advantage to using one for the extraction of alkaloids. lyse, acid-base chemistry.

Do you consider continuous heavy phase liquid-liquid extractions soxhleting?

no.
soxhlet is solid-liquid. CLLE is entirely different, something i'd like to acquire as I don't have an app for it.
most are set up for use with haloforms, since they are heavier than water..it's rare to find a lighter-than-water setup.

You can get a setup that does both...

or get a gregar extractor.

I saw one the other day that was designed much like a soxhlet , it had a collection tube that allowed for light phase extraction.

What I do personally when pulling into a light phase solvent, is I'll pour my light phase solvent into a glass burette with somenglass beads. Then drip the heavy phase down into it, often tying a hand warmer around the upper portion of thensolvent.

I'll allow the heavy phase to build up and open the stopcock so that the addition/sep funnel and burret release the heavy phase at an equal rate.

Works alright.

nice. how much?
the cheapest i've seen is ~$549 , and that doesn't include the aux. condenser.

They wanted me to call them for a quote, probably 3-500. Either way I have enough soxhlet condensers to not need to worry.

sell 'em and get a sonicator

I got one for 500ml capacity but I've only used it once x)

a sonicator?
that bad boy will reduce extraction times 9-fold, at least.

i prefer to use that over the soxhlet, no question.

sonicate a dilute acidic sol'n, vac filter, basify, extract, and rotavap. all that can be accomplished within an hour.

So I can just sonicate a citric acid mixture, vac filter into a sep funnel (I have a jointed filter) , basify with alkaline solution, mix in my solvent, dump the bottom / chloro layer, rotovap, extract with dilute heptane, clean with a tiny amount of AC, filter, centrifuge, reduce solvent volume/warm it, and cool slowly..

I should have a brilliant field of clear needlepoints within hours :3!

Having the right tools for the job rocks !

yep, sure does.

hey guys what do you think about the ethanol extraction of alkoloids with a soxhlet? it's a good tek? Do you suggest any solvent instead of ethanol? acetone probably?

Keep in mind you are trying to dissolve acidic alkaloids. Not every solvent will play the part. It *will* work, but other methods work better.

indeed.

simple A/B extraction?

yes.

There is one advantage I see using a soxhlet, and that is for an acid/water boil. It has the benefit of separating you bark from the liquid, simplifying the filtration part of the process. But soxhlet money would be better spent on a vac filtration/sep funnel setup.