I understand that they are not the same but that they are similar in structure. I've seen that some of the metabolites of elemicin are quite similar to mescaline as well.

Just read about their mix being pleasant. That's interesting, and I saw the difference with the E: dream like visions mixing with the M: "visuals" which is a nice place to start but really, qualitatively, please someone describe the difference in the headspace affect best use case?
I'm interested in these things medicinally and would really like to understand typically what each's strengths and weakness' are.

Check this thread, wherein the key to all phenylpropene-related threads lies.

It's not clear whether elemicin and/or its metabolites are FAAH/MAGL inhibitors; that would certainly influence its therapeutic indications.