I've tried 100mg harmalas 20 minutes orally before mescaline hcl rectally (the same I do for dmt). Then another dose of harmalas about 90 minutes later. Can't say it amplified the state, so I am not using it anymore with mescaline, only if dmt is on the way. I was targetting non-psychoactive harmalas dose though, so maybe higher doses might influence the state more. And this "combo" seemed to be safe, no negative effects, so I don't see reason why not redose harmalas throughout the experience if it works for you.
Acceptance of the fact that our reality is not real doesn't in fact mean it is not real. It just leads to better understanding what real means.