Presuming all MAOI precautions are taken - would anyone care to share how often (for those who take harmalas quite frequently and for a very long period of time) and what works best in general? Dosage, timing, gradual increase/decrease, combinations with other substances (i.e. microdosing)... whatever you think is relevant.

I suppose nausea goes away, there’s a general improvement in mood & harmine works best in terms of clarity and body load?

I've been dosing small amounts (10-30 mg or so) sublingually before bed with melatonin at roughly the same dosage pretty much every night for around 3 years now. It's been a great experience. Dreams are intensely vivid every night, I wake up feeling well rested, refreshed, and ready to meet the day. I've noticed a lot of the same benefits as reported from microdosing other substances: improved mood, increased creativity, heightened awareness and flexibility of thinking, etc.

The reasoning behind taking it at night is that it aligns with the bodies natural processes. When you go sleep your body stops producing serotonin and starts producing melatonin which is metabolized into pinoline and sets off an endogenous cascade of production of other beta-caroblines and tryptolines throughout the sleep cycle.

A few times a month or so I add a little microdose of psilocybin to the nightly harmela.

The daily low dosing does seem to make things go more smoothly with larger doses when I drink ayahausca or take full/psychedelic doses of harmala. There is certainly a level of adaptation that takes place in regards to nausea/bodyload/vertigo effects, not to be confused with tolerance, harmalas (at least for me) seem to exhibit a strong reverse tolerance.

I won't recommend this regimen for everyone, I'm very much a guinea pig here, but thus far my results have been nothing but positive and I do intend to continue the experiment long term.

I have been doing microdosing , sometimes for 3 weeks in a raw. Also 10 to 30mg. But i took it in the morning, as i wake up, before a morning meditation. I found that it works mostly with intention - the effect is in fact really subtle. But it allow me to "reset" my consciousness many many times in the day, and come back to the awarness of my body and feelings, my posture and breathing (farming becomes more a form of chi kung exercice). I get easily traped in the dayflow in general, so this allow me to step back for a second and make me more "centered", bringing the benefits of meditation in daily life.

When i did it for 3 weeks, i felt a form of "build up" of the Harmal spirit, enhancing wisdom and greater thoughts. In a way, it can also bring more "work" to the surface.

I never felt anybody load, and the bitterness became kind of a nice thing, having a immediate effect, as the body recognise the power of the medicine.

I "accidentaly" snack on tiny aborts of Cubensis, which then sometimes make much more effect than expected. But not sure it's link to the harmal, as any microdose of tryptamine can make unproportional effect on me.

The post above inspired me, and as i'm starting to microdose again, i will try it at night (i think, i did it in the morning because full dose of harmala make me extremely relax, but NOT able AT ALL to sleep. but a microdose is another story, so we will see)