Ah yes, the psilocybin treatment!
I remember Dan.
That's why I'm so grateful for DMT and the subculture that has been born around it. It was this community that sparked my interest in chemistry, which taught me about the structural similarities between all the substituted tryptamines. It was ClusterBusters.com that helped me understand that I even had a disease, thanks to the underground psilocybin research that was just blooming 12 years ago when my headaches started. I was reading about mushrooms as a young lad, and Erowid led me to an article about medicinal use of mushrooms, and wham-o, I found a perfect description of the headaches I was experiencing (I thought it was a stroke or a tumor or something).
So naturally I got some shrooms and tried the Cluster Busters regimen. Didn't work for me. The thing about psilocybin treatment is it prevents future attacks for many sufferers, but requires several weekly doses to do it. It can end or significantly dampen a cycle. Same goes for LSD and LSA. None of those 3 were effective for me, so I always thought of psychedelics as just an exploratory tool.
Cluster Headache is treated in two ways: preventative and abortive. Try to prevent future attacks, and try to stop a current attack. Psilocybin/LSD are preventatives (now being legitimately studied! Yay!), but they didn't seem to do it for me. Nothing I tried would prevent future attacks, and very little could be done to abort an attack.
Well since the psilocybin treatment didn't help me, I figured I'd just be stuck with this forever. I have probably damaged my kidneys and liver with repeated high doses of acetaminophen, ibuprofen, aspirin, naproxen, hydrocodone, morphine, dilaudid, cocaine, tramadol, carisoprodol, clonazepam, darvocet, just off the top of my head... None of these ever helped much if at all, but in the throes of a cluster attack you'll be willing to try just about anything. It's pretty annoying to have a pain that comes and goes in 1-2 hours when most oral medications take an hour or more to kick in. Chances are, the headache will subside on its own and you've just unnecessarily ingested chemicals for your body to metabolize. Placebo effect is a joke when it comes to this condition, you can't fool The Beast.
In my quest for DMT knowledge, I learned that it's only a few atoms away from psilocybin. LSD and LSA are also remarkably similar, all of them are based on the indole structure and are believed to affect the same receptors. So an internet search about DMT and cluster headaches led me right back to the Nexus, where somebody had posted about his experience. He said his girlfriend suggested DMT (based on the same correlations) while he was having an attack, and he laughed at her, thinking the last thing he needs right now is to blast off. Well she loaded the apparatus for him and left the room, he said screw it and took the hit, and was amazed to find that his headache was gone with a snap, crackle, pop, before the elves and fractals could even materialize. This gave me hope, but it was during a time that I had a lot of fear about this stuff... the "more real than real" trip had given me a big respect for what this stuff can do to you, and I too was thinking the last thing I need while in pain is to possibly be surrounded by improbable monsters. I know about set and setting, so it's very counter-intuitive for me to take such a strong drug in such a situation.
I remember the day I tried it. I woke up in the morning with The Beast thrashing wildly in my skull, and I stumbled out to the kitchen to get some Tylenol. I ground up 1000mg and put it in capsules, hoping it would dissolve and start working faster. I think it did, because 15 minutes later the headache ended pretty abruptly. I thought I had found the secret! That's all you gotta do, crush up a gram of acetaminophen! Boy was I wrong though... an hour later the Beast came back with a vengeance, what is known as a Rebound Headache. I went back to bed, this time knowing I shouldn't take more acetaminophen because it hadn't even approached its half life. I lay there in tears, wishing for death, and then suddenly I figured... how bad could a DMT trip be? I realized that this was my first bad day since the scary DMT trip 3 days prior, there might be a correlation there.
I took a hit of (guessing) about 20mg, and as my bedroom erupted into a cacophony of fractal train tracks and animated musical scores, I saw an entity appear in front of me. Oddly enough, it looked like a certain doctor I work with, and it reached a hand out and touched my face. I felt a pressure quickly build inside my head, akin to driving up and down a mountain road. The pressure grew until my ears popped, and then there was a crack that I heard and felt around the base of my skull. And then the pain was gone. The "doctor" stayed with me until the trip ended, and I lay there in tears of joy, thanking the concept of God that I hadn't believed in for over a decade (I now believe there's SOMETHING).
No rebound this time! I couldn't believe it, in 30 seconds I went from wanting death to loving life, the pain wasn't just reduced or masked, it was GONE! It didn't come back when the drug wore off, as it always had with all other drugs. This drug did something specifically to the headache, it left me speechless. For the first time in 12 years, I knew that I wanted to live.
Since then I've lowered the usual dose. I work far from home, so I do a lot of driving. I work in a medical setting, so I have to keep all of this stuff to myself. It's dangerous to drive under the influence of anything, but especially something that makes you see things the rest of us can't see. I kept trying smaller and smaller doses, as I want to kill the pain without having to break from reality. Well I've found that the smallest threshold dose (inhale for <5 seconds and hold for 10) can almost always abort a headache for me. I've found a dose that I can safely use at work, or on the side of the road. I'd much rather pull over or hide in the bathroom for 10 minutes, than drive or even try to think while the Beast is active. Once in a while I intentionally use enough to explore the fractal realm, but it's nice to know that at different doses it's good for different purposes.
Long story short... mushrooms are good for the long term, DMT is good for instant relief. Some people who don't respond to psilocybin may still respond to DMT. I want to shout it from the rooftops, but I don't want to draw the wrong kind of attention to myself (and the rest of us) either... so I figure this is the best place to start.
The best contribution I can make here is to tell you all, that you have the power to heal. And to thank this community for sharing that possibility with me.
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