Hi there dear humans!
SWIM put his hands on large amount of san pedro pachanoi.

SWIM drying it in food dehydrator as is (core and waxi layer include) and then put it in a blender and boy its days of working until the task gonna be done, but a labor of love

SWIM already try 69ron d-limo vinager tek and He was very pleased! altho he would like to extract pure white crystals! he also thought about hcl extraction as well.
SWIM estimate that he will have about 10 lb of drying pedro and want to extract mescaline.

SWIM is wondering which tek will be the best to deal with this amount for pedro.
Please help SWIM to choose the yieldest way to extract the cacti and to become A SIR PEDRO!!!

Hi there,

I would go this route for extraction with this route for purification

If you wanted more info, just let me know

do you think that its would yield more and purer then 69ron Hcl D-limo?
SWIM really like the foodsafe tek but D-limo is very expansive and for this amount of pedro...
did you try other teks like KASH's tek and others?

No, I am listening to and following my inner source of information. I am satisfied with results it is advising to me so I don't feel urge to try anything else.
I suggest anyone to do the same. Anyone should follow such feelings. If you think foodsafe techniques are good for you, go this way. If you feel you should use anything else, do so. Anyone doing the opposite is more likely to go the wrong way.
I believe in lab-grade chemicals, pure techniques and knowledge. Using semi-toxic chemicals is not a problem for me when I understand the principles and know/feel they are left behind in the process.
I like the foodsafe techniques in common, I just feel it is not easy to hit the water/dry material ratio and I don't like the separation of np when using the ron's technique. I understand excessive water amounts in STB are not good as the solubility of mescaline freebase is quite high in water (compared to dmt freebase for example), but still I think use of NaCl and proper pulls minimize the negative effects.
Anyway, I cannot guarantee how this technique with NaCl will react with D-limo, so if you don't want to undertake the risk and you insist on using D-limo, use another tek. If you decide to use STB, I strongly suggest using toluene, as it is tested. Any (seemingly small) change of the technique can have vast impact on the result

Just wanted to chime in on how to save money with D-limo: You can reuse your solvent pretty much indefinitely if you are salting out the alkaloids to create mescaline (HCL, sulfate, or acetate etc. etc.). The end result depends on what acid was used. This means you could, in theory, do all your pulls with the same initial amount of D-limo.

Pull --> Salt out the alks --> Pull --> Salt out the alks --> Repeat until your heart is content.

You can even wash your solvent after you are done extracting with basic water and acidic water to remove soluble impurities. This has saved me a ton of money over the years because D-limo is expensive, like you said. It may be a bit more time consuming to do it this way, but worth it in the end, in my opinion. You could always speed up the process by doing 3 pulls, combining said pulls, salting out the alks, and repeat with same solvent. The same principle can be applied to other solvents as well. See here for more info:

On reusing non polar solvents

Good luck!

I tried Kash's tek twice with mixed results. I also encountered lots of emulsion.

An alternative to using excess base is an alcoholic extraction. It works very well with ethanol and methanol (IPA almost doesn't work). Ethanol is best in terms of toxicity of course.

One can then perform A/B extraction on the alcoholic extract with less acid, base and solvent.

The downside is more labour and equipment needed.

Maybe try to precipitate like this


Endlessness said



I will being trying this next to see how pure I can get the mescaline without a MEK wash. This is the whole thread.

pete666,SWIM really belive in following your exitment in every thing in hes life, also apllied about extractions

SWIM has done josh tek for spice and harmala extraction many time before and prefer foodsafe but have no problem extracting with other solvents.
so basically SWIM want to have the yieldst and purer xtals and all ways are kosher

TGO, SWIM try to base the limo 3 times with s.carbonate but it didnt change anything, acid wash anyhow he didnt do yet, He did do his reaserch about recycling the limo and the glassware are little expansive for him at this moment, but its somthing in his wishlist anyway
about the reuse of limo, 69ron write about this subject, he said that when you use the limo more then 4 times its will pull less alkaloids, and also he said to do 3 pulls of acid with limo and then to add NEW limo and do the same.

blue.magic, theres some confusion about alcohol ext.
did you meant to pull with ethanol insteed of acid?
SWIM asking if this will be the best way for extraction with your knowladge?

JP, thank for the replay, thats sound good the combining of the aceton (purification) and the acid (pull) to a one prosses and save time.
SWIM will research this prosses a bit more.

69ron:
You could reuse the same d-limonene. But not more than a few times because it's going to reduce yields as it gets saturated with chlorophyll and other crap from the cactus. I think you could probably use the same d-limonene at least 4 times before discarding it.

That is interesting, however, I'd like to share my own experience, which is a bit different than Ron's.

Over the past few years, I have used the same d-limo. I purchased a gallon and it came in 4 quarts. While using 69ron's tek, there will almost always be some loss of solvent that gets absorbed into the basified mixture. So, except for topping off the pulls with a little extra d-limo here and there, I've been using the same batch of d-limo for around 10 extractions, with at least 4 pulls being done for each one. After a couple of extractions, I wash the solvent. It still remains yellow/greenish from the cactus, but it definitely still pulls mescaline effectively.

At this rate, I will run out eventually, so it isn't completely foolproof. But it does last a lot longer than using 300ml of fresh d-limo for each pull. That is why I mentioned previously that you can use it "pretty much indefinitely", if you wanted to go that route. I encourage you to experiment to see what you come up with and post your results, no matter which tek you decide to go with.

I love d-limo. I just bought another gallon of it. It's such a great cleaner as well. I've been buying vintage botanical prints and framing them to hang on the walls. D-limo cleans glass very good, I use it to get adhesive from price stickers off the frame glass. Once I'm finished using it for extractions I'll use it for cleaning. I don't know how many pulls I have on the old d-limo but it still smells like oranges and cuts through glue great. I'm sure I could do more pulls with it but I think I'll save it for special cleaning jobs.

when SWIM will finished the dehydration and powdering of the cacti he will start the extraction, SWIM aslso order all kinda glassware to upgrade his kitchen so anyway he will start the extraction in 3 weeks or so..but in the meanwhile he will try some of the teks
right for this moment SWIM probebly go for 69ron hcl tek, if anyone try this tek and have sucsess\unsucsess please shere, and if you can get pure white hcl PLEASE SHERE!

SWIM really wants to shere some photos when he gonna exract but he affreid about loading stuff to the internet and not sure how to do it and stay anonymous..
thanks for the teaching guys, SWIM will update asap!
much love~!

Ok guys swim is almost done with the dehydration and the glassware has arrived!! whiiipppiiidooo

now swim read's A LOT about all kind of extraction teks and have some quastions regarding soxhlet extration with ethanol/methanol.
swim saw this extractions: https://www.reddit.com/r/Drugs/comments/14egu0/i_got_got_a_pound_of_dried_san_pedro_skin_to/ tek and this https://mycotopia.net/topic/52607-a-different-approach-to-cactus-extraction/ tek,
also he read about other people that use soxhlet.
in the 2 ext above, both use soxhlet/reflux with methanol as solvent and both yield 10mg/gram meaning 1g of mescaline from 100g dry matirial witch is A LOTTT!
swims cacti probebly not as high quality as others so he belives he will yield less then others.

Swim thinking about buying soxhlet for many many uses(even for non-psycodelic herbs) but he also see that people having problems with this kind of extraction.

blue.magic can you explain in more detail the soxhlet ext?
also how much dry powder will fit in soxhlet? the biggest swim's see is 2000ml but regulary they 250/500/1000 ml, and that is probebly why the tek i linked above use reflux...

no one have any answers or shering regard soxhlet/reflux??

Well, likely not what you want to hear, but I am a happy owner of soxhlet aparatus and honestly, I wouldn't use it for mescaline. It is not proved to work, I've read about some attempts, but they either failed or had doubtful results. I may be wrong, it is some time I was doing the research, but I don't feel this is the right path.
If you are bored by being successful many times with STB or A/B, then yes, go ahead, do the research and try it. But if your aim is successful extraction with high yield, I would suggest sticking to proven techniques.

swim saw that the soxhlet extraction has done by blue.megic with great sucsess of about 1% yield.

swim thinking that even the largest soxhlet will fill probebly 200 grams or so of cacti poweder and he has about 4.5 kilo to extract which gonna take some time...
so swim thought about reflux extraction with 5 liter boiling flask and a reflux condencer to deal with the amount ot the cacti estimating of couple extraction to finish the job

10l glass (suggested borosilicate with PTFE cap - I bought it for 100$) bottle can do 750g of dried material for STB
With two such bottles you can do everything within 3 extractions
But if you insist on soxhlet, maybe blue.magic will have more information

pete are you reffering somthing like this?

anyway swim ment a reflux with 5 liter boiling flask and condencer not soxhlet, for the methanol extraction

Yes, but this is PP cap likely. Whether you need PTFE depends on the np used. I remember you were considering d-limonene, but I don't know how compatible it is with PP. I suggest toluene and there PTFE is a necessity. My cap is red - I am using : Reagent bottle SIMAX with red cap. The borosilicate is not necessary, but it is less attacked by NaOH. I did few extractions with soda-lime glass and it is ok too. I just feel better with borosilicate.

I see with the soxhlet, anyway, I can help just with STB.

I would have got me one of those stainless conical homebrew fermenters, blended all of that whole cactus fresh and mixed it with %20 by weight of lye. Then added solvent and used the fermenter as a giant separating funnel the next day Works very well for large extractions the only key is to keep it hot at 80 deg and use a paint mixer on a drill for basing and for mixing in solvent. You need the heavy mechanical action to migrate the freebase.

That’s the fastest most stress free way for bulk extraction