If you bear with me, I'm going be to trying the alcohol to resin to cleanup route and posting my own experience with it in mushrooms workthread over the coming weeks, since I have some PF cakes just been dunked and in the fruiting chamber at present. All is not lost joshisom

please let me know your progress

me too

Just a note, that may also help other that haven't tried the procedures you link in your OP yet, if you filter out these crystals and let them dry, you'll end up again with a sticky mess and, of course nowhere pure psilocybin or psilocin.

I totally understand that seeing white crystals precipitatinge out seems magnificent and you immediately start thinking hell yeah...it is however deceptive. As benzyme noted above, there are tons of other things (normally present in mushrooms and extractable with alcohol) other than actives that can precipitate out of the alcoholic tincture. And just as "crystallic precipitate" does not mean "isolated compound", "white" does not necessarily mean "pure".

Maybe he was using methanol not ethanol...

Looks like I forgot back then to follow up on a cleanup method involving rinsing with many solvents to pull away non- active material from goo. If I recall it involved chloroform, acetone and some other solvents. The result is supposed to be a grayish powder, but I don't even know if it's active. Even if it works, the result will still be impure, and is still a lot of expense and effort, not to mention a big waste of solvents. I just must have just thought 'nah...screw that'.

I've been wanting to try the following for some time. Outline:

1) Cold 70% Ethanol soak of dried ground flesh of the gods. Use sulfites to avoid oxidation instead of vitamin c (available at brew shops for wine makers)
2) Centrifuge at 4000 RPM (or filter?) Set supernatant aside for step 4.
3) Repeat 1) and 2) a few times on what is caught by the centrifuge (or filter). Test residue and verify no activity after a few ethanol pulls (<-- this part may be fun)
4) Combine all ethanol pulls. A reducing/re-filtering step may make sense here. If this is evaporated a goo will probably result (?). Instead, of fully evaporating add | High Pobability of Braindamage by Creepy non tested Drugs (forced by scammer 69ron) | and then evaporate.
5) Result after drying may be crystalline | High Pobability of Braindamage by Creepy non tested Drugs (forced by scammer 69ron) | complexed with psilocybin (and other small molecules). This is why we use sulfites in step 1) to avoid possible (but not sure) complexation with vitamin C which would waste | High Pobability of Braindamage by Creepy non tested Drugs (forced by scammer 69ron) |.
6) Clean up with dehydrated acetone (| High Pobability of Braindamage by Creepy non tested Drugs (forced by scammer 69ron) | is not soluble in acetone, I don't know if complexed | High Pobability of Braindamage by Creepy non tested Drugs (forced by scammer 69ron) | would be, assuming no for now)

A variant could be to use acetone before complexation which may give a cleaner product after the final acetone wash (would only work of psilocybin is soluble in acetone). We'd be taking advantage of the transition to (supposedly) non-solubility in acetone after complexation.

Any thoughts? Thinking of starting this work next week. If this has been tried and results exist, or there is a reason someone can identify for this not working, let me know. My apologies if I missed such thread(s) despite my search efforts.

There are a lot of unkowns. None of the info above is factual, just musings which may all prove to be wrong upon experimentation.

Here's hoping you have made progress with this, Loveall! I come back to this thread so often whenever someone quotes the 'xtals of the gods tek' and it's wonderful to see that people are still trying to do good science based experiments on psilo extraction.

Thanks. It didn't quite work. But we keep on learning and trying.

I struggle to find any reliable extractions of psilocybin or psilocin.

here's a reliable extraction method:

cut up your psilocybin mushrooms, pour boiling water on them, let sit for a few minutes and you're done: your psilocybin/psilocin mix is now in the water (which you can consume if you're into such things and if it's legal where you are ).

Go out in nature and do a "pull" with your fingers.. Then basify by chewing hard.. Then you need to "salt it down" by swallowing the base. You could also skip the "pull" by simply stand on all four and eat them like a tiger!

that's not the point. the point is the process, to satisfy scientific curiosity. psilocin extraction is one of the more challenging ones, due to its instability.

I stand corrected on this. trehalose is one of the compounds found naturally-occuring in some fungi, and may end up in aqueous/alcoholic extractions. phosphatase enzymes are also present, and responsible
for the conversion at pH <4, under mild heat (40C). they give the extract its greenish color.

I'm aware of the point and I encourage all efforts. Sadly, basically all efforts thus far have proven unreliable. Seeing as this has been going on for years, I'm not very optimistic. At this point it just makes more sense to obtain 4-ho-met or 4-aco-dmt if you want a relatively stable crystalline powder that's a prodrug for psilocin, although that's another discussion.

These are jokes.. eat a mushroom and relax! Or do some science

I do science, all day everyday. May have some during a vacation, when I have time.

it’s been done, and published, just not with the kitchen utensils people are accustomed to.
A turkey baster won’t cut it for this one. One must use the art of separation science.

Good, a role model! One day I will build my own lab.. and probably then blow my self up! until then I will enjoy the more abstract "Tha Bastard in the kitchen separation"

Well, we seem to be able to get to (nor)Baeocystin now. Not perfectly pure, and yield is unkown, but it's something. I'm sure we'll get more progress and go further with benzyme.

Now I have enough dried fruits to experiment with (250 grams ). I am still preparing for the 3-step washing of the alcohol extract I call A-B-C to remember easily: Acetone, Benzene, Chloroform.

The latter two are harder to obtain but can be made from easily obtainable items (sodium benzoate, household bleach) with some safety precautions.