DMT-Nexus member
Posts: 13 Joined: 30-Apr-2017 Last visit: 08-Mar-2020
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I’m currently taking a medical treatment but I’m not sure if it is compatible with harmalas.
I take Xanax, this one seems ok. But I take an other one called Athinyl, it’s miansérine. A sedative that acts as an anti depressive at 30mg, it helps me to sleep.
I asked the doctors but they were not able to tell me if it’s safe to take an MAOI with this.
I asked them if mianserine is a MAOI too thinking that it’s what i have to avoid, but I think that the right term is SSRI.
The doctor was just able to tell me that the Athinyl plays a role in serotonine level.
Can anybody help please?
Any natural alternative to these drugs maybe.
Changa helps a lot but i still have anxiety and sleep problems.
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DMT-Nexus member
Posts: 13 Joined: 30-Apr-2017 Last visit: 08-Mar-2020
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I have checked list 1 and 2 in the pinned post. I found no references about all that.
I don’t even know if my molecule is a SSRI.
It’s classed as: Other: Anti-depressive. Not just anti depressive it’s a bit weird to me.
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Boundary condition
 
Posts: 8617 Joined: 30-Aug-2008 Last visit: 07-Nov-2024 Location: square root of minus one
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So, no changa for you. Also, the half-life is up to 61 hours so you really should wait at least 15 days after last use of mianserin before considering using MAOI substances. Furthermore, if you have mental health issues powerful psychedelics might not be the best thing for you. They are not some kind of magic wand which fixes you just because you use them. “There is a way of manipulating matter and energy so as to produce what modern scientists call 'a field of force'. The field acts on the observer and puts him in a privileged position vis-à-vis the universe. From this position he has access to the realities which are ordinarily hidden from us by time and space, matter and energy. This is what we call the Great Work." ― Jacques Bergier, quoting Fulcanelli
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❤️🔥
Posts: 3648 Joined: 11-Mar-2017 Last visit: 02-Jun-2025 Location: 🌎
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According to this Mianserin is a tricyclic antidepressant. Apparently you don't even want to mix it with St John's Wort. eMC wrote:Features of serotonin toxicity may occur. These include CNS effects (including agitation or coma); autonomic instability (including hyperpyrexia); and neuromuscular excitability (including clonus and raised serum creatine kinase). This syndrome is more likely to occur if the patient has been exposed to two or more drugs that increase the effect of serotonin in serotonergic synapses (by increasing release, reducing reuptake or metabolism, or stimulating serotonin receptors), either as an acute overdose or if taken regularly, for example - SSRIs, MAOIs, tricyclic antidepressants, venlafaxine, tramadol, triptans, linezolid and St John's Wort, stimulant drugs of abuse (e.g. MDMA (ecstasy), amphetamines, cocaine, cathinone derivatives (mephedrone, etc).
The cardiovascular and CNS effects in overdose will be potentiated by simultaneous ingestion of alcohol, cardiovascular agents and other psychotropic drugs.
I feel like your doctor should have told you this, especially when you asked 
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Pay No Mind
Posts: 934 Joined: 28-Dec-2014 Last visit: 26-Jan-2021 Location: 40th Parallel
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Loveall wrote:According to this Mianserin is a tricyclic antidepressant. Apparently you don't even want to mix it with St John's Wort. eMC wrote:Features of serotonin toxicity may occur. These include CNS effects (including agitation or coma); autonomic instability (including hyperpyrexia); and neuromuscular excitability (including clonus and raised serum creatine kinase). This syndrome is more likely to occur if the patient has been exposed to two or more drugs that increase the effect of serotonin in serotonergic synapses (by increasing release, reducing reuptake or metabolism, or stimulating serotonin receptors), either as an acute overdose or if taken regularly, for example - SSRIs, MAOIs, tricyclic antidepressants, venlafaxine, tramadol, triptans, linezolid and St John's Wort, stimulant drugs of abuse (e.g. MDMA (ecstasy), amphetamines, cocaine, cathinone derivatives (mephedrone, etc).
The cardiovascular and CNS effects in overdose will be potentiated by simultaneous ingestion of alcohol, cardiovascular agents and other psychotropic drugs.
I feel like your doctor should have told you this, especially when you asked Doctors don't know. You always want to ask a pharmacist these kinds of questions. The pharmacists are trained to know this kind of stuff, doctors are not. Freedom's so hard
When we are all bound by laws
Etched in the scheme of nature's own hand
Unseen by all those who fail
In their pursuit of fate
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❤️🔥
Posts: 3648 Joined: 11-Mar-2017 Last visit: 02-Jun-2025 Location: 🌎
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Yes, pharmacists are a great resource, but shouldn't the doctor also know about interactions? Maybe it depends on the country? https://www.medicinenet....rt.asp?articlekey=17046#
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DMT-Nexus member
Posts: 13 Joined: 30-Apr-2017 Last visit: 08-Mar-2020
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downwardsfromzero wrote:So, no changa for you. Also, the half-life is up to 61 hours so you really should wait at least 15 days after last use of mianserin before considering using MAOI substances. Furthermore, if you have mental health issues powerful psychedelics might not be the best thing for you. They are not some kind of magic wand which fixes you just because you use them. Thanks for clarification, i won’t take more mianserine. I know what you mean about psychedelics, I consumed 200+ acids, a lot of K and 2CB, bromo dragonfly etc... But spice helped a lot. I always feel better after and i can bring back things from these trips into hyperspace. My depression was triggered by chronic pain a few months ago. I started spice let’s say a year before. Everything goes better with it. My vision of life is way different and better now. But thanks for the advice, I would not take some LSD now for exemple.
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DMT-Nexus member
Posts: 13 Joined: 30-Apr-2017 Last visit: 08-Mar-2020
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Loveall wrote:According to this Mianserin is a tricyclic antidepressant. Apparently you don't even want to mix it with St John's Wort. eMC wrote:Features of serotonin toxicity may occur. These include CNS effects (including agitation or coma); autonomic instability (including hyperpyrexia); and neuromuscular excitability (including clonus and raised serum creatine kinase). This syndrome is more likely to occur if the patient has been exposed to two or more drugs that increase the effect of serotonin in serotonergic synapses (by increasing release, reducing reuptake or metabolism, or stimulating serotonin receptors), either as an acute overdose or if taken regularly, for example - SSRIs, MAOIs, tricyclic antidepressants, venlafaxine, tramadol, triptans, linezolid and St John's Wort, stimulant drugs of abuse (e.g. MDMA (ecstasy), amphetamines, cocaine, cathinone derivatives (mephedrone, etc).
The cardiovascular and CNS effects in overdose will be potentiated by simultaneous ingestion of alcohol, cardiovascular agents and other psychotropic drugs.
I feel like your doctor should have told you this, especially when you asked Wow!!!!!! Thanks for the link. I’m going to have to find something natural.
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DMT-Nexus member
Posts: 13 Joined: 30-Apr-2017 Last visit: 08-Mar-2020
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I’ll wait for 15 days and try a bit of caapi daily.
Do you have any caapi form to recommend for depression?
I have Muricata leaves.
Maybe X30 extract??
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