Hi all,

I will like to share with you what happen to me so hopefully wouldn't happen to you.

I took 450mg of pure harmala from rue, two times and serious dehydration happened. This is only when increasing harmalas, dmt dose doesn't pose a threat, this could be a different topic.

1. Time

The trip was endless, but afer three hours of journey, I started to sweat abnormally, for one hour, the sweating wouldn't stop, and when it did I started to feel weary hot, but I could drink water, and my sitter was cooling me with cold towels.

I knew that this sweating was wrong, doing pharma for 7 years more or less monthly.

2nd time

Well this was much worst. The sweating reappeared. BUT I couldn't drink water. After sweating stopped and my body temperature started raising. I was yawning a lot, much more than in normal situation.

I knew that I lost liquid and electrolytes, so in the country where I live it's possible to buy IV bag with electrolytes and vitamins. After administering it I wa OK in half hour. Had it not been the case, I would had to go to ER.

I can elaborate more if needed but I would say, NEVER go over 400 mg or 350mg.

Best to all
Danko

Yeah there's no need for that much imo. I usually stick to 180mgs to 200mgs of freebased Rue or freebased Harmala extract, and i like to take it regularly so with the reverse tolerance the dose gets stronger each time. Dehydration and dry mouth can definitely happen with Harmalas, also especially if one is vomiting a lot or has diarrhea.

I remember my heavy harmala trials and they were the most relentless brutal trips

After 7 years of pharma you could have known what the result would be? I'm a little surprised about you being surprised.

Yesterday I was surfing the net and stumbled on this page (that was actually too much for me to understand all the science language.)
Exposure Characteristics of the Analogous β-Carboline Alkaloids Harmaline and Harmine Based on the Efflux Transporter of Multidrug Resistance Protein 2
140mg/kg ??? That must be an error? Because some lines later they speak of 5 to 15 mg/kg in other animals. I understand 5 mg/kg that would be 350 mg for my weight and a bit of my uterrrrrrr maximum, same as your conclusion.
I really feel for these lab animals

Hi Jees,

You are my mentor btw. So thank you, all I learned was from you.

Why would you think I would know what would have happened. The trip was no the problem, on the contrary.

The problem was the dehydration.

I think people should be aware of this, what is dehydration, that it can cause hart failure, and what are electrolytes.

I could have been in ER situation had inot had access to IV and my knowledge how to do it, even though I was in deep trip.

The article is very complicated. And it must be mistake with numbers. I will try to read it again... But it was interesting that no toxicity has been found, in live rats.

I also wonder how different it is if taking harmalas alone and adding dmt. I don't think it's the same.

Best Danko

P.S.

It would be another entry on why I decided to increase the harmalas. I don't think many people have any knowledge nor interest in this topic, this is vap in cite after all.

Thank you for the compliment, yet the real mentors are those who output the chemical knowledge to make an extract, I've merely tried to make workflow fast and easy.

Thanks for detailing on the hard part, I've never had such effects myself luckily and never heard of such complications tbh, so it's good you put it here for the record.

And you are right that adding spice to the harmalas gives another kind of journey, you'll love it.

Blessed be!