Is it possible to microdose every day and on some days take even lower the dose to keep tolerance in check, but how long could this last?

And what effects should one notice during this microdose? Just asking to make sure to get the dosage right

How long can you continuously microdose?

I have also researched and gone over all the safety precautions using mushrooms for depression.
I have been using psychedelics responsibly for the past 2 years all without problem and think now I should try microdosing as I read it can be more effective at treating depression.

I'm also asking about microdosing any psychedelic.


Thank you.

Hello, So many questions, and with possible answers, I want to be careful answering you.
Are we talking situational, financial, geographical, mild melancholia depression, or a diagnosed bio-chemical depression ?

Micro dosing is an option for depression as is getting a bicycle !
Your question is rather like 'Is oxygen going to cure my breathlessness.

"The red oil light comes on as you are driving. If you fiddle with the wiring you can make the light go out. No light = no problem, right ?'

With DMT and the integration of the experience, it can change you, its not a regular pharma cure all. Its not just another psychedelic only stronger.
However, back to your questions, micro dosing, you may feel a powerful surge of intellectual prowess and your vocabulary will increase ten-fold. Be careful taking the Red pill.

Now, back to the depression, have you tried cutting sugar from your diet ?
Regards G

Cutting sugar, riding a bike, good suggestions for sure.

If, if you have tried other things, and feel you need some sort of pharmaceutical aid, micro dosing is far better than taking SSRIs in my opinion.

That said, for me the whole point is NOT taking anything every day, but only using a short regimen to kick start me out of a depressive episode.


You too?

How depressed are you? I have lifelong issued with mono polar depression. I just saw it get REALLY bad. Classic psychedelics were out of the question. I was too far gone. I had to seek out ketamine therapy. A risky endevor for people with addiction, but a miracle for people on the verge of suicide.

Microdosing for depression does not work for me. If I am moderately depressed, microdosing seems to make the episode last longer and go deeper with more anxiety. LSD and Psilocybin both do this to me. Mescaline seems to work, but it's rarely around. I need to buy a sep funnel and a respirator so that can change.

I had great success with daily dosing of caapi extract, sublingually. Adding DMT to the mix on a daily basis was great at first but nearly precipitated a manic episode. that's what I thought at least. A friend and psychiatric pro told me I wasn't manic, just using too many psychedelics. In her words, I had gone too far into bliss. It was just as bad as depression. I have lost the ability to extract caapi for some reason. Rue extract makes me anxious even at 10mg sublingual. I think it's the lack of THH. I need to learn to make THH from Harmine. I think people on here have figured it out, but I doubt it's something you can do in your kitchen.

Mushrooms are the most reliable solution to keep my depression/anxiety in check. In order to keep the good effects rolling I need approximately 8-10 full experiences a year. Two, a week apart, every three months for me.
LSD doesn't seem to have the same ability to help my depression, although I did completely eliminate lower back pain for an entire year with an intentional LSD trip.

I need to explore ayahuasca for depression. Still haven't done a real brew.

Also see,

"On micro-dosing Ketamine and Depression"

here:
https://www.dmt-nexus.me...aspx?g=posts&t=77969

You too?[/quote]

Yes indeed.

Interesting observations. I have a mono polar diagnosis although not sure I agree with it, but I can definitely relate to deep,long episodes.

Interesting that you don't find relief from md regimens, I find that a couple weeks semi regular with .25-.5 g dried cubes to really help me move out of a long symptomatic episode.

Never worked with the other substances you mention, although I did try using Syrian rue as an anti depressant a while ago, not micro but macro doses for about a week and it seemed to cause the same sort of anger and rage that SSRIs do to me.

It might sound a bit tame but have you tried 5-HTP
I suffered from depression for the best part of 2 years. 5-HTP worked surprisingly well even tho it's just a supplement it definitely lifted the clouds

Very much agree with this. Diet and exercice are essential. What is nice was that, for me, microdosing brought natural focus to my diet and exercice.

I am vastly more grateful for microdosing than Zoloft (or really the whole psychiatric "help", no magic in them medications, no spirit. However, do not abuse it or you will get worse! Taking it everyday is impossible, you will end up very anxious and schizoidial. There is as much integration as for larger dose. A microdose I could steel feel the next day, so find you rythme, go with the recommended schedule by Fadiman if you want to be square (and you need to). It might be tempting to take more than is needed, because it can enhance you in some great ways. I dosed LSD and I think it might be more tiresome for the mind and the body than other substance (I want to try mushrooms soon).

It had some great effects for me, so I hope it will for you too. Low dose of psychedelic are still sacraments, very much so. If you go with respect, everything should go as the wind blows. There has been some thread going on here about microdosing with nice and detailed report, check them out.

You will have to find out what works for you. Mental health illness is a very individual thing. Different people respond differently to different agents. Sometimes the remedy can be worse than the illness itself. One of the greatest strengths of modern medical practice yet also one of its major flaws is the almost slavish devotion to evidence based practice.

Evidence based medicine is great at finding out what works for most people but doesn't tailor treatment for individuals based on their unique circumstances. Good doctors are supposed to do this based on the evidence available but increasingly, it has been dumbed down to following a protocol set by some expert group. If you throw into this mess the fact that most of the studies on which the evidence is based are sponsored by drug companies who are trying to sell their products and the increasing prevalence of non medically trained healthcare practitioners who would get crucified alive if they deviated from protocol; it gets very murky indeed.

Certain treatment options (e.g ketamine as Mister_Niles has already described) have shown a lot of promise but no major drug company will sponsor a large study to gather evidence as it is off patent and there is no money to be made from it.

The best you can do short of finding a very good psychiatrist genuinely interested in you is

1. Start keeping a diary your moods and possible triggers.
2. Start with simple measures like healthier lifestyle (diet, exercise, regular sleep etc)
3. After a few months of this if your diary doesn't show objective improvement try things like meditation, breathing exercises etc.
4. If your diary still doesn't show any changes and conventional treatment is not working for you, consider microdosing.
Set yourself a protocol (days of the week, dosage and duration of trial).
Do not deviate from your protocol unless there is a complication.
At the end of your trial period look at what evidence your diary shows.
Be aware that there will be a large degree of observer bias / placebo or nocibo effect. I would suggest ignoring the placebo effect if it works for you (do you really care as long as it makes you better).
Something worth doing is making note of craving, temptation to break your rules etc in your diary. If you find this is happening stop using the drug immediately. Depression and addiction is far worse than depression alone.

Finally, take my advice (and everyone else's) with a huge pinch of salt. After all we are random faceless strangers. I hope you get better, All the best.

Stay away from Medical/drug treatments altogether.

1 Cold showers
2 Good Diet
3 Get a bicycle
4 Change your environment to suit your bio-chemistry, not change your bio-chemistry to suit your environment


Advice from a faceless stranger.....

ps. It is no measure of health to be well adjusted to an insane society.

Regards
G

Hi all,

I can go on on this topic a lot, since I am serious mourning, and Belem micro and full dosing.

In micro dosing do it 3-4 x a week.

More will cause you anxious, manic, nervous. Well maybe not at first but eventually it will. If that is the case take kava.

I do it at 4-5 in the mourning, alarm clock.

But I recommend Lacanian psychoanalysis, it's the best of all.

But also you have to do a strong dose first,

Then, I would microdose dayly with Iboga.

And few times a week with pharma. However you must know your need/tolerance of harmalas. If you need higher amount on real trip for micro you would need more, and vice versa.

Best to you
Danko

Lots of good ideas in this thread. Cold showers, healthy diet, excercise, I couldn't agree more.

I'd like to add WATER to this list. It is essential to your biochemistry. I often think, if humans were cars, food would be our gas and water our oil. It cleanses us, refreshes and lubricates our brains for smooth operation. Note: I always drink non-fluoridated water.

Growing up, I wasn't taught the importance of hydration, food and sleep. I would often neglect them in search of drugs. The drugs helped ease my depression, but little did I know much of it was caused by simple bodily needs that I was ignoring.

Don't ignore your body. The discomforts you feel are messages that it needs something. Try to be strong and healthy. Breathe deep and take in your surroundings; always be present. And, as others have said, take all this with a grain of salt.

This is priceless advice IMO^^^^^^^^^^^^^^^^^^^^^^^^

From what i understand
The tolerance of Lsd-25:
y= x/100*280.059565*n^-0.412565956
The y value represents dosage needed for same effect, the x value represents last dosage taken, the n value represents the number of days since last trip.
*there are calculators.
when doing this study are you trying to feel the trip entire time? Or are you using it as a tool to be able to heal. Using a dose that works for microdosing I feel should be giving you the effects of mind opening. I dont think living in a world of the trip would be good for healing in this way. Get a big batch of one that makes you feel like your eyes are open. Figure out your own dosage. My dose was about 12.5 mics.

The way I did it was four months on a planned method. Your best bet in safety is to get a a full hit and the amount your planning on doing the entire time. My plan was I would take the doses every day for the first month. Then every other day for a month. After that I was to go down to twice a week. once a week.
When i got everything that I needed (vitamins and a routine) I took a whole hit to really break away emotions i couldnt work through with out a mental tool that allowed me to think about blockages.
Then a week later I started with approximately 12.5 micrograms. I took a hit of blotter and tore the front and back apart from each other. Then tore those to quarters. At this dose its not enough to feel "trippy" it was however enough to allow me to be able to look at things happening inside outside and around me in different eyes.
In the first month I took it seemed to be like I could understand a little better. Why I was sad but also how to help myself through hard points. At this point my friend scotty died. A few days after I took a whole tab and went into a bad trip. I saw him dead every time my eyes closed. I saw his head split and smashed with that goofy grin he always had. I thought about what he meant to me and what the things were i loved in him and how i could bring that to myself. That BAD trip really was no bad trip but a giant blockage being broke down. After that i continued to treat.
After that i felt healed. I contiued to ease myself off the lsd as was still planned. I have since not laid in my bed wondering how im going to kill myself. I have not thought about all of those bad things.
I know some people dont get what depression is but its a lot more than just being sad. Its being frozen every day. Wishing it will end and being mad at yourself for being scared to go through with it. Then mad at yourself for thinking it. Knowing you can do so much but fail everything.
Some times you need tools to help. Lsd is a gift from god to help us with these things in all honesty i truely believe that. It always shows up when I cant handle life any more. So I tried it as a medicine and it worked.
Be safe. Be healthy. Be happy.


Formula and description source: https://www.reddit.com/r..._calculator_and_formula/

I haven't tried that but I think 30mg in the morning and the same dose 1 hour before bed could help you be a little more relaxed and go through the motions of the day while the real cause of depression is being worked on.