https://www.dmt-nexus.me...aspx?g=posts&t=21695

I'm having the same issue as OP in that post. There's a few threads on here, but I can't find anything definitive on the plant. There's just conflicting anecdotal information. Does it make dmt orally active? Or is it like drinking caapi-only brews? Any conclusions on the toxicity of harmane? It grows literally surrounding my house so I will probably bioassay it at some point this winter. Does anyone have any experience(s) they'd care to share on this plant?

No it does not activate oral DMT. It's very similar in effect (and taste) to a caapi brew. I've not noted any toxic effects even at fairly substantial doses (~500 g of bark).

Traditional extraction methods don't seem to work very well on this one, either due to having a different spectrum of harmaloids, or simply the exceedingly low alkaloid content.

My notes on my extraction methodology and bioassay results can be found in that thread you linked starting at post #176.

This is by no means a replacement for caapi or rue, but I suspect there may be potential MAO-B inhibition going on and that it might be worth (carefully) exploring with cactus/phenethylamines.

The plant that I have worked with that grows in my area is Autumn olive, Elaeagnus umbellate .
I can say for certain that it is active indeed .
I have tried a few different extractions from the leaves and bark . I've even made jam from the berries wich are technically fruits because they have only one seed. It's considered an invasive species in my state and it grows everywhere .
I have done alcohol soaks of leaf and bark material . I have made changa blends using it . The most interesting stuff was a manske salt extraction on bark material . It yielded a fine Grey powder that was definitely active. It had a wild synergy with spice and I might even go as far as to say it has its own trip quality by itself. It can have some super weird and sometimes scary effects for sure. The leaves can also be active as well . My feeling is that it's not as refined as Ayahuasca in its effects but still a strong plant teacher more like an untamed wild animal . I think there are some very different varieties of Russian olive out there that I guess have different alkaloid contents. The Autumn olive thats in this area is a prime candidate for some kind of analysis . I've been wanting to have checked out for years now .