IME, harmalas do indeed significantly potentiate LSD, Mescaline, DMT, and Psilocybin/Psilocin containing mushrooms. In each and every trial, they significantly potentiated the psychedelic experience, prolonging effects by upwards of 2-6 hours, as well as smoothing-out and grounding the experiences, serving as guides to harness the psychedelic energy in a manner similar to how the harmalas in an Ayahuasca Analog may guide one through the experience, grounding oneself before the psychedelic thunderstorm and utilizing the energy/light to teach me lessons which would have otherwise remained illegible and unnoticed if they weren't there. When I combined them, I noticed that ~100-200 mg of harmalas with a 100-200 micro-grams of LSD would have the power of a dose twice, if not thrice that, as well as extending the duration from 8-14 hours to ~14-18 hours. Taking ~50-100 mg of the P. Harmala extract the day afterwards seemed to attenuate the burnout/fatigue which I typically experience for a day or two after the experience. This has held-true for experiences with mescaline cacti, too.
In essence, imagine LSD to be a raging thunderstorm/hurricane with lightning running rampantly throughout my body. Harmalas seem to harness the electricity and convert it into a smoothed-out lesson on life.
I have not taken it with MDMA, and hopefully never will (for obvious reasons). Neither have I combined it with any other semisynthetic psychedelic tryptamine/phenylethylamine analogues.
I have noticed that smoalking a harmala-heavy changa blend whilst on 200mg of R-modafinil did not induce any ill effect. When I accidentally ingested a small quantity of harmalas (25-50 mg) 3 hours after taking 30mg of racemic amphetamine sulfate (PO), I didn't notice any ill-effects, nor any indication of a hypertensive crises or serotonin syndrome. Although
I HIGHLY RECOMMEND NO ONE COMBINE HARMALAS WITH ANY AMPHETAMINE WHATSOEVER, this accidental combination seemed to produce little more than a slight calming effect, as well as prolonging the effects by 3 hours more so than normal, as well as diminishing the ill effects of the comedown, smoothing-out the decline so as to gently glide back down into my typical scatterbrained mentality in lieu of crashing back into it. I have no intention of EVER combining harmalas with these psycho-stimulants in the future, but was surprised that a these RIMAs didn't induce any of the ill effects commonly observed from these combos.
I hope these experiences help,
-Godsmacker
'"ALAS,"said the mouse, "the world is growing smaller every day. At the
beginning it was so big that I was afraid, I kept running and running, and I was glad
when at last I saw walls far away to the right and left, but these long walls have
narrowed so quickly that I am in the last chamber already, and there in the corner
stands the trap that I must run into." "You only need to change your direction," said
the cat, and ate it up.' --Franz Kafka