Hi fellow members!
I was searching around for a while on whether or not yopo seeds can be orally active by themselves or if you need a MAOI, and from what I found everyone seems to have their own opinion about this. Some say you need a MAOI, some say you don't, some say yopo seeds doesn't work orally at all and some say they only work at a very high dosage. If anyone has any experience with oral yopo use it would be very interesting if you could share it.

The nausea is very bad with oral use , once you start getting past a few seeds . I'm sure there is a way around this but I've never found it , I don't prefer this route , extraction and traditional administration is what I prefer with ceblil , which is what I use , but yopo is pretty similar , almost it's equipollent.

If one can get past the stigma of rectal ROA, this seems to work very well for yopo/cebil and avoid any nausea. I made a tea from 8 cebil seeds void of skins and a pinch of citric acid and reduced it down to 10 ml and plugged it with a syringe. The experience lasted about an hour but I didn't feel entirely sober for a few hours. There were mild visuals and heavy body load. I felt hot early into the experience, but the thermometer said it was all in my head.

Besides the nausea, do you get similar effects compared to snorting/smoking it?

I do not like yopo or in my case cebil very very much , the bufotenine in both raise my blood pressure it seems , which normally happens with my aya use anyway but it's more pronounced with my cebil seeds so I'll only use a couple with maois and add something else like viridis , or other bark , but I also do not like too many additives in general so on the rare occasion I do I try only a couple to a few tops , I have extracted crudely I may add , an extraction to add to maois but I just generally don't like that method of ingestion , if I have seed powder I have roasted and ground it is usually snuffed , I deal with the pain , for me ironically it isn't too bad, not sure why, I have sinus issues so maybe the blockage keeps the pain lower , dunno, many folks hate snuffing , however there are great tek s for extraction. I can vouche only for using and trying that roa once . It was worthwhile , but I normally have other projects so I would do that again only it's not a priority for me atm. There are benefits to bufotenine but I generally choose something else before it just bc of high blood pressure concerns on my part like I mentioned above. Those seeds are potent though so becareful, big difference between a few seeds and nine or ten , and their small size is deceiving. However some folks have had weak seeds, that s never been my case . Still some degree of nausea with snuffing too, just seems to be a part of it, someone else here may have a better way to avoid the nausea , I'm sure they ll chime in. Good luck , also I always snuff a single or couple seeds of a batch first to see how potent they are I recommend this for you too no matter what . And my effects for snuffing are generally faster , the peak higher and shorter and harder to absorb than oral use , which despite its less high peak is more rewarding for me solely because I can integrate the experience better , I feel the same with dmt, I generally like it better with an oral route and Maoi just so I can "keep up" with the whole thing . Plus I'm a big fan of caapii so it's win win for me. I try to use the cebil snuff as a fast teacher or healing on occasion becuase of its faster dissipation sometimes . But it's usually because I have less time to myself as I'd like , there are pros and cons to both . Hope this helped some , interesting the rectal roa, I think I've heard about that approach before , I'm positive it has benefit just never tried that

Sublingual is also a good method if you don't swallow the juice , but I have not had much success with that as others

I took about 15 drops of lemon oil to reduce nausea (as anectodal evidence suggests) and then drank 5 grams of crushed yopo seeds (peeled) with calcium carbonate (functioning as antacid) - 1:3 ratio.

There was no nausea, it was sedating and pleasant experience, no visuals. I felt refreshed afterwards.

The necessary amount to be eaten is however too high (several grams at least to feel considerable effects).

It seems that things like lemon EO that reduce nausea by inhibiting or tying up 5-HT3 receptors, also have the effect of reducing or eliminating visuals. When I mixed 16mg Ondansetron with pharmahuasca (100mg DMT) the visuals dropped to nearly zero. This amount would have normally been a rich visual experience.

Unfortunately, bufutenine is definitely a 5-HT3 agonist and any ROA involving the mouth or nose will eventually bleed a small amount into the stomach if enough is taken to cause visuals. If you like being nauseous while tripping, go for it. Otherwise, think about ROAs that avoid plumbing close to the stomach.