Forget my first post. I'll edit it.

I thought that I somehow got 5-Meo-DMT N-Oxide because my 5-Meo-DMT fumarate was inactive via sublingual administration.

Then I found a post of 69ron recommending to mix the alkaloid salt with calcium carbonat to keep the pH of the mouth high, making the 5-MeO-DMT absorb faster.

I didn't have calcium carbonat at hand, so I just blended 10mg 5-meo-dmt fumarate with 100mg soda-bicarbonat (baking soda).

It worked!

The effects went from ZERO effects to FULLL psychedelic effects.

As soda-bicarbonat is water-soluble it's suited for working with a ticture.

I'll do a test with calcium carbonat (with isn't water soluble) soon and make an 1:1 comparison in potency.

I wonder if soda-bicarbonat (or soda-carbonat) or calcium-carbonat would also help with sublingual-dmt-harmala (and even nasal) administration? I love the sublingual route and normal nn-dmt is working here without basing the mouth-mucosa. Maybe adding a base would allow to decrease the nn-dmt+harmala dose to 1/3 of the normal dose.

I'll keep you posted about my experiments.

If someone has anything to contribute experience and knowledge to all of that, I would much appreciate that.

Still wondering though how people get 5-meo-dmt salts to work sublingually without a base.