I here of people who have smoked 5 MeO DMT. I've skimmed through the Wiki for 5 MeO sources and I can't seem to find a decent source for it and the ones that do have a bit have other stuff in them. What is the source for 5 MeO that people are smoking and how are people separating it from the other alkaloids that are present? Pursuing something like this would be very interesting but I don't even know where to start.

I would also be curious if there are any commonly accessible ways of isolating alkaloids from one another after doing an extraction from plant sources such as phalaris grass or yopo
I would primarily be concerned with 5 MeO DMT, bufotenine, and DMT.

I believe most of the reports you read are of people using either synthetic 5-meo or bufo venom. I recall reading somewhere recently that 5-meo-dmt is still legal as a research chemical in canada, it could be BS though, i never checked into it further.

The above was posted by 69ron

Virola theidora is certainly a way. But nowadays it seems, it's very very hard to find any good anymore (read many reports of people getting bunk material). Also you have to be aware that it seems, to get it, they usually kill the trees. So from an ecological POV IMHO not an option.
Additionally it is illegal in some countries.

IMHO Pilocarpus Organensis could be another good source but is literally impossible to get.

Bufo certainly seems the "easiest" way, but my morality detector wouldn't allow me to keep them in captivity.

There also seem to be some Acacias which could be interesting. But there the climate could be a problem, as anyways is the case with most of the plants.

That's why I personally now try to go the phalaris way (as it really grows in almost any climate condition). But as it seems that is a very tedious one...(if only there was a seller for "Turkey Red" seeds)

AFAIK there hasn't yet been found a way for an easy separation of 5-MeO-DMT and DMT (although there are some indications that e.g. DMT dissolves better in naphta than 5-MeO-DMT). So if a plant contains both you would have to use a column.
The sublingual way of 69ron is, as I got it, only for low dose application. 69ron didn't like dosing high on 5-MeO-DMT.

But currently it really seems, as has been said, that the 5-MeO-DMT people use is mostly either from Bufo or synthetic.
Any 5-MeO-DMT you can buy online is basically always synthetic. That's quite the opposite to DMT, where it seems most of the DMT sold is MHRB extracted.
And yes, I heard also that it is legal in Canada. But that seems to be a very rare exception nowadays as it is certainly illegal in many countries.

Edit:
E.g. this post from 69ron himself shows that it seems already back then in 2008, finding usable virola was very difficult
(https://drugs-forum.com/threads/virola-theiodora-resin-dosage-and-5-meo-dmt-content.68192/)

I have heard of the bufo venom but I have heard of people smoking straight 5-meo. I have never heard of sythetic 5-meo. That is very interesting. Do you have any idea how involved that process is to create it?

Ah! I vaguely remember McKenna talking about Virola resin. Your subligual idea is awesome! This is great info! Do you have any idea why 5 MeO is active this way? Do MOAs not have an effect on 5-MeO possibly?

Oh and also just to clarify are you administering Virola resin sublingually? I think traditionally it is done in the form of snuff.

They just dont call it synthetic. Overwhelming chances are what youve heard referred to is indeed synthetic from an RCco. Or venom.

I feel 5meoDMT is singular in its capacity for transformative experience, but its not easy to come by like n,n DMT. Maybe thats for the best, idk.

Just post twice

Just post twice

MOAR

MOAR

Yes, as has been said, if you encounter 5-MeO-DMT today in powder form you can be almost sure it is synthetic.
AFAIK the problem with most of these trypt synths is not the difficulty of making them. But that there's basically always one step needed: the alkylization (e.g. adding the N,N-dimethyl). And all the stuff with which you could do that is a watched chemical, not available for normal people (and many of them quite hazardous substances).

5-MeO-DMT was in many countries much longer legal than e.g. DMT. But around the 2000s this changed. And sometime ago it has been made illegal in China, and since then the market almost collapsed.