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Trazodone and DMT Options
 
Proxima Centauri
#1 Posted : 4/23/2016 10:15:35 PM
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Has anyone had any experience with this drug interaction? I was recently prescribed Trazodone for sleep issues. I have read the stickied post that it may decrease the effects, but I was wondering if anyone here has had any first had experience.
 

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vitriol
#2 Posted : 12/4/2016 11:04:15 AM

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Leithen
#3 Posted : 12/4/2016 5:13:02 PM

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wulong84 wrote:
I am taking Trazodone for two weeks for sleeping issues and depression which I had from childhood and start to be serious after ending of problematic relationship. When it is antagonist of 5-HT2 receptor it is probably not good to smoke dmt when person is on Trazadone. If it is true I want to know how long I have to wait after not taking Trazadone to smoke dmt or changa. If anyone from the forum taken this medication I want to know the opinion. It seems to helpful to me.

I took Trazadone when I was younger and it always gave me very strange and vivid dreams. Most of them were quite scary. Shocked

Although I never took DMT while on it I may have some insight to your question. According to https://www.ncbi.nlm.nih.gov/pubmed/6764164 the half life of Trazadone is 1 hour and has an elimination half life of 10-12 hours. If you were to skip one nights dose I would think the following day you would see full effects in the DMT.

Sorry I can't speak from experience but hopefully this helps!
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vitriol
#4 Posted : 12/4/2016 6:19:45 PM

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