I have often noticed that a few days after taking LSD, i start developing mild rashes. A friend of me had the same thing happening to him. I also remember having read somewhere that rashes are a common side-effect of ergometrine, a lysergamide.

I've never read anywhere that LSD actually does this, and maybe it's all just a coincidence, but has anybody else ever noticed something like this?

I wondered that too, back when i took my last lsd trip i had rashes too, but i was just starting at a new workplace at that time that exposed my arm to various oils and chemicals so i thought it was because of this.

vasoconstriction may be a factor...

LSD causes vasoconstriction, possibly more sensitive individuals will experience skin irritation as a result of this vasoconstriction?



An example of Skin irritation (destruction) produced by ergot
(*Ergot and the compounds it contains are far more severe than anything LSD could do, this is just an example of skin irritation due to vasoconstriction produced by consumption of lysergamides, I'm not implying LSD can cause ergotism*)

-eg

I don't know if the vasoconstriction itself has anything to do with it. Maybe though, constriction of the pores of the skin, could cause rashes.
It could also be more complicated. As LSD has dopaminergic as well as noradrenergic effects, it could also be cortisol related. Or maybe LSD activates the thyroid. I've Always found that the infamous so-called 'electric taste' is more a weird sort of electric feeling in the throat, around the thyroid area, than an actual taste-like sensation.

I always assumed the "electric" deal started with owsley stanley and Ken kesey...

Here's my thoughts on this "electric" nomenclature in the LSD community:

...as well as being the grateful dead's sound engineer, owsley was also a notorious clandestine chemist specializing in LSD, "white lightning" was was an owsley classic brand of LSD...

Owsley also designed the "steal your face" logo for the grateful dead, a clear reference to "white lightning LSD", which also helped to cement this "electric" association with LSD in the public mind.

owsley, as a chemist, would know that Pure salts of LSD are triboluminescent, a phenomena which is said to be related to electricity...



So, as really pure LSD will emit flashes of white light, when shaken, in the dark, I always assumed that "electric" was simply referring to very pure LSD, as this phenomena occurs with it...



So, then this "electric" term for LSD spreads from the chemists, to a public who doesn't understand the physical compound or its chemistry, this could have happened in part by kesey labeling his vats of LSD laced kool-aide for the "acid test" events as "electric" to designate it from the kool-aide which was not laced, so the public gets this name "electric", but as they are not chemists, and as they have not seen pure LSD crystals, they can't understand where it came from, most people even today are unaware that pure LSD crystals are triboluminescent... so the public assigns its own meanings to the term, telling others "good acid will taste or feel electric" because they figured that's what it must have meant, this causes a psychosomatic synesthesia in the people who hear this, just by expecting it, they experiance it...

Ok, back to the topic:

If this rash was related to Dopaminergic or Adrenergic aspects of the pharmacology of LSD, then you may expect to see similar reactions with other Dopaminergic or Adrenergic compounds, no? Maybe a place to investigate...

The pharmocological properties of LSD are not fully understood, but from what we do understand, and from the research that has been done, I can only remember hearing of this "skin irritation" from LSD in this thread, and from a single anecdote on another site...

I'm still guessing it's a vassoconstriction issue, but really can't say anything for sure.

I posted a graph showing receptor site agonism and affinity for the receptors regarding LSD, though I'm not sure it's very relevant to this thread...

-eg

Below is a picture of "necrosis" caused by ingestion of a large but unspecified quantity of bromo-Dragonfly, ( 1-(8-Bromobenzo[1,2-b;4,5-b]difuran-4-yl)-2-aminopropane ; Bromo-Benzodifuranyl-Isopropylamine ), this necrosis was a result of severe vassoconstriction induced by consumption of bromo-dragonfly, and similar to your claims, the article states

This is why I feel vassoconstriction is the most likely cause, but again, I can't sayanything for suren

It shouldn't, IME.

It all depends on the quality of the blotter though. Lower grade tabs are known to have a much more pronounced body load. Cleaner stuff is mainly just a head high.

Even though clean acid is golden, I can't say I haven't had fun on dirty too. Because of the body load it seems more intense at time sometimes changing the direction of the trip. It also has a more drugged out feeling, but you can clearly tell it is the same drug altogether.

Being that said, if you can try to source cleaner stuff you never know if those trace chemicals are actually damaging to your health or even some sorts of poison (ergot is poisonous).

The rash shouldn't be caused by vasoconstriction. It is relatively mild when synthesized properly, be careful and test it if possible if those stuff is noticeable enough to make you worry.

No i don't think it's related to vasoconstriction either. The rashes i had didn't look anything like those pictures.

This is consistent with the vasoconstriction caused by bromo-Dragon-fly and related compounds...and seems inconsistent with LSD, as rashes are not reported.



Bromo-Dragon-fly is active between 200 and 800 micrograms, it is commonly sold on blotter, and is commonly sold as LSD...

It's 100% OK to not agree with me...

I just see many consistencies with bromo-Dragon-fly and the side effects associated with it...

If I was told that story with the name of the substance removed, I would assume it was regarding bromo-Dragon-fly rather than LSD...

Rash is not a common symptom of LSD...and the only means by which the related ergotamine-ergocristine alkaloids compounds are known to affect the skin is by vasoconstriction...


-eg

No, yours would not look like that, that was a very severe case...Maybe a bad example...

-eg

Well, okay, i've had some of these rashes after having taken shrooms as well...So maybe it is related to vasoconstriction then.