This is pretty basic stuff but if i smoke syrian rue will i still have to watch my diet and such? I suspect the answer is yes but nothing would be going into my stomach so who knows? If someone were to smoke rue and then take a gelcap of DMT would it be active?

I would stay away from pharmaceuticals but you do not have to watch your diet. the MAOI's in your stomach would not be fully inhibited by smoking rue (or extract).

Most people will tell you that with Rue and Caapi you do not need to watch your diet (unless it is part of a spiritual preparation).

Oh no kidding, but I guess that means SWIM wouldnt be able to take the DMT orally after smoking rue extract. Still that could be good to potentiate Snuff? or non oral methods of ingestion? Good stuff, SWIM generally errors on the side of caution with these things so in the past SWIM was always worried about everything SWIM ate before hand.

Thanks

ever try smoking rue seeds while on psilocybin? works wonders for swim, and is almost instantaneous.

I take clonazepam (A benzo I believe), should I not take caapi or rue because of this? And does anyone know of a good thread for beginners guide to what to take with spice? Ive never taken anything besides spice and small amounts of shrooms and salvia a few times and ive only heard about MAOIs from this forum (the only forum I visit) so all this is brand new to me. Some beginners help would be greatly appreciated...

When doing research on interactions with harmala alkaloids DO NOT LOOK AT OLD MAOI RESEARCH, look at new RIMA research. Harmala alkaloids are RIMAs, not full blown MAOI compounds. They are much safer. This is why ayahuasca often contains things forbidden to use with MAOI compounds, because ayahuasca only contains RIMAs.

RIMAs are Reversible Inhibitors of MAO subtype A. Most other MAOI compounds are not RIMAs, they are not reversible, they permanently destroy MAO and are many times more dangerous. For example, eating aged cheese high in tyramine is relatively safe when using RIMAs, but can kill you if you’re using normal MAOI compounds.

So is caapi and rue considered MAOI or RIMA? and maybe SWIY can suggest a newbie friendly combination?

Caapi and Rue are RIMAs only.

I am not a Dr and do not give medical advise. If you stick with recommended dosage and NO booze you should be fine. You should still do your research because you cant believe what people say especially these days information is zooming all over the place with little time for fact checking.

Good luck

PEACE
MV

Definately wouldnt do anything without more research.... but certain people on this forum I have come to respect such as 69ron and yourself (and a few others). So you guys giving me a starting point is great! Thanks for everyones responses though

I would do some research and check if clonazepam is safe to use with moclobemide. Moclobemide is a popular pharmaceutical grade relatively safe RIMA, and not a full blown highly dangerous MAOI. If a dangerous interaction exists between clonazepam and moclobemide, then likely the same would be true for the harmala alkaloids (harmine, harmaline, THH, and harmalol) and plants containing them (rue and caapi) because they have essentially the same RIMA actions as moclobemide.

Apparently moclobemide is sometimes prescribed along with clonazepam, so the combination of a RIMA with clonazepam seems to be safe enough for doctors to give to patients.

SWIM knows all about super fragilistic benzos dancing on the head of the pin by the five hundreds lot

Fragilistic obdoses was suckin down bu KU BE nzos in enormous no interactions for me 150mg big V not much but relax.

high tolerance OVER AND OUTTHERE

This took place in another space and time

it is a dream locked in the past(or is it) said and done
interesting experement!
relaxing too.........



No prob found
yeah code................................


MV

Very cool 69Ron, ill check into that myself....thank you

Glad to hear everything went alright with you too MV

can one smoke the seeds as is powdered,or does it need to be freebased? I have a friend that is on methadone for pain and adderall for ADHD should he avoid taking rue,or would he be fine if he didn't take his medication for some period before use?